Combined approach to the inverse protein folding problem. Final report

Abagyan, Ruben A.

New York University School of Medicine, New York, NY (United States)

关键词: Forecasting;    Genes;    Functionals;    59 Basic Biological Sciences;    Proteins;   

DOI  :  10.2172/761120
RP-ID  :  NONE
RP-ID  :  FG02-96ER62268
RP-ID  :  761120

美国|英语

来源: UNT Digital Library

【 摘 要 】

The main scientific contribution of the project ''Combined approach to the inverse protein folding problem'' submitted in 1996 and funded by the Department of Energy in 1997 is the formulation and development of the idea of the multilink recognition method for identification of functional and structural homologues of newly discovered genes. This idea became very popular after they first announced it and used it in prediction of the threading targets for the CASP2 competition (Critical Assessment of Structure Prediction).