Enhancing the Benefit of the Chemical Mixture Methodology: A Report on Methodology Testing and Potential Approaches for Improving Performance

Yu, Xiao-Ying ; Yao, Juan ; He, Hua ; Glantz, Clifford S. ; Booth, Alexander E.

Pacific Northwest National Laboratory (U.S.)

关键词: Chemical Mixture Methodology;    Emergency Management;    Protective Action Critieria;   

DOI  :  10.2172/1079750
RP-ID  :  PNNL-21248
RP-ID  :  AC05-76RL01830
RP-ID  :  1079750

美国|英语

来源: UNT Digital Library

【 摘 要 】

Extensive testing shows that the current version of the Chemical Mixture Methodology (CMM) is meeting its intended mission to provide conservative estimates of the health effects from exposure to airborne chemical mixtures. However, the current version of the CMM could benefit from several enhancements that are designed to improve its application of Health Code Numbers (HCNs) and employ weighting factors to reduce over conservatism.