DCE Bio Detection System Final Report

Lind, Michael A. ; Batishko, Charles R. ; Morgen, Gerald P. ; Owsley, Stanley L. ; Dunham, Glen C. ; Warner, Marvin G. ; Willett, Jesse A.

Pacific Northwest National Laboratory (U.S.)

关键词: 77 Nanoscience And Nanotechnology;    Dna;    Biological Materials;    Fluorescence;    Bio-Detection System;   

DOI  :  10.2172/1023141
RP-ID  :  PNNL-17213
RP-ID  :  AC05-76RL01830
RP-ID  :  1023141

美国|英语

来源: UNT Digital Library

【 摘 要 】

The DCE (DNA Capture Element) Bio-Detection System (Biohound) was conceived, designed, built and tested by PNNL under a MIPR for the US Air Force under the technical direction of Dr. Johnathan Kiel and his team at Brooks City Base in San Antonio Texas. The project was directed toward building a measurement device to take advantage of a unique aptamer based assay developed by the Air Force for detecting biological agents. The assay uses narrow band quantum dots fluorophores, high efficiency fluorescence quenchers, magnetic micro-beads beads and selected aptamers to perform high specificity, high sensitivity detection of targeted biological materials in minutes. This final report summarizes and documents the final configuration of the system delivered to the Air Force in December 2008