First-Generation H1 Antihistamines Found in Pilot Fatalities of Civil Aviation Accidents, 1990�2005

Sen A, Akin A, Craft KJ, Canfield DV, Chaturvedi AK

FAA Office of Aerospace Medicine - Civil Aerospace Medical Institute

关键词: Forensic Sciences;    Toxicology;    Pilot Fatalities;    First-Generation Antihistamines;    Antihistaminics;    Aviation Accident Investigation;   

RP-ID  :  DOT/FAA/AM-07/12

美国|英语

来源: Federal Aviation Administration

【 摘 要 】

First-generation H₁-receptor antagonists are popularly used for alleviating allergy and cold symptoms, but these antihistaminics cause drowsiness and sedation. Such side effects could impair performance and, thus, could be the cause or a factor in accidents. Therefore, the prevalence of these antagonists was evaluated in aviation accident pilot fatalities.