Analysis of Cocaine, Its Metabolites, Pyrolysis Products, and Ethanol Adducts in Postmortem Fluids and Tissues Using ZymarkTM Automated Solid-Phase Extraction and Gas Chromatography-Mass Spectrometry

Lewis RJ, Johnson RD, Angier MK, Ritter RM, Drilling HS, Williams SD

FAA Office of Aerospace Medicine - Civil Aerospace Medical Institute

关键词: Forensic Toxicology;    Cocaine;    Pyrolysis Products;    Zymark;    Cocaine Ethanol Adducts;    Aircraft Accident Investigation;   

RP-ID  :  DOT/FAA/AM-03/23

美国|英语

来源: Federal Aviation Administration

【 摘 要 】

Cocaine (COC) is one of the most widely abused illicit drugs in America. COC abuse transcends all social, racial, and economic boundaries. Following the introduction in the mid-1980s of a new form of cocaine called �crack,� cocaine use has been on the rise. Because of its intense �high,� crack smoking has become very popular. Despite its popularity, crack smoking is a particularly dangerous form of COC use. Additionally, COC and ethanol are frequently used together, resulting in the formation of a biologically active molecule that is nearly as psycoactive as COC but produces a longer lasting and toxic effect.