An Accurate Method for the Determination of Carbon Monoxide in Postmortem Blood Using GC/TCD

Lewis, R.L., Johnson, R.D. and Canfield, D.V.

FAA Office of Aerospace Medicine - Civil Aerospace Medical Institute

关键词: Combustion Toxicology;    Carbon Monoxide;    Carboxyhemoglobin;    Methemoglobin;    Aircraft Accident Investigation;   

RP-ID  :  DOT/FAA/AM-02/15

美国|英语

来源: Federal Aviation Administration

【 摘 要 】

During the investigation of aviation accidents, postmortem samples from accident victims are submitted to the FAA�s Civil Aerospace Medical Institute for toxicological analysis. To determine if the accident victim was exposed to an in-flight/post crash fire or faulty heating/exhaust system, the analysis of carbon monoxide (CO) is conducted. While our laboratory predominantly uses a spectrophotometric method for the determination of carboxyhemoglobin (COHb), we consider it essential to confirm with a second technique based on a different analytical principle.