Analysis of Carbamate Pesticides: Validation of Semi-Volatile Analysis by HPLC-MS/MS by EPA Method MS666

Owens, J ; Koester, C

关键词: CARBAMATES;    ENVIRONMENTAL PROTECTION;    HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY;    MASS SPECTROSCOPY;    METRICS;    PERFORMANCE;    PESTICIDES;    QUALITY CONTROL;    SECURITY;    US EPA;    VALIDATION;    WATER;   

DOI  :  10.2172/945575
RP-ID  :  LLNL-TR-403969
PID  :  OSTI ID: 945575
Others  :  TRN: US200904%%91

学科分类：化学（综合）

美国|英语

来源: SciTech Connect

【 摘 要 】

The Environmental Protection Agency's (EPA) Region 5 Chicago Regional Laboratory (CRL) developed a method for analysis of aldicarb, bromadiolone, carbofuran, oxamyl, and methomyl in water by high performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS), titled Method EPA MS666. This draft standard operating procedure (SOP) was distributed to multiple EPA laboratories and to Lawrence Livermore National Laboratory, which was tasked to serve as a reference laboratory for EPA's Environmental Reference Laboratory Network (ERLN) and to develop and validate analytical procedures. The primary objective of this study was to validate and verify the analytical procedures described in MS666 for analysis of carbamate pesticides in aqueous samples. The gathered data from this validation study will be used to: (1) demonstrate analytical method performance; (2) generate quality control acceptance criteria; and (3) revise the SOP to provide a validated method that would be available for use during a homeland security event. The data contained in this report will be compiled, by EPA CRL, with data generated by other EPA Regional laboratories so that performance metrics of Method EPA MS666 can be determined.