Preimplantation genetic diagnosis for gender selection in the United States

Colls, P. ; Silver, L. ; Olivera, G. ; Weier, J. ; Escudero, T. ; Goodall, N. ; Tomkin, G. ; Munne, S.

关键词: 59;    CHILDREN;    DIAGNOSIS;    EMBRYOS;    ETHICAL ASPECTS;    GENETICS;    MALES;    ORIGIN;    SEX RATIO Preimpantation Genetic Diagnosis;    gender selection;    FISH;    ethics committees;   

DOI  :  10.2172/983213
RP-ID  :  LBNL-3378E
PID  :  OSTI ID: 983213
Others  :  TRN: US201014%%589

美国|英语

来源: SciTech Connect

【 摘 要 】

Preimplantation genetic diagnosis (PGD) of gender selection for non medical reasons has been considered an unethical procedure by several authors and agencies in the Western society on the basis of disrupting the sex ratio, being discriminatory againsts women and disposal of normal embryos of the non desired gender. In this study, the analysis of a large series of PGD procedures for gender selection from a wide geographical area in the United States, shows that in general there is no deviation in preference towards any specific gender except for a preference of males in some ethnic populations of Chinese, Indian and Middle Eastern origin that represent a small percentage of the US population. In cases where only normal embryos of the non-desired gender are available, 45.5% of the couples elect to cancel the transfer, while 54.5% of them are open to have transferred embryos of the non-desired gender, this fact being strongly linked to cultural and ethnical background of the parents. In addition this study adds some evidence to the proposition that in couples with previous children of a given gender there is no biological predisposition towards producing embryos of that same gender. Based on these facts, it seems that objections to gender selection formulated by ethics committees and scientific societies are not well-founded.