Occurrence of hepatitis A virus in Philippine cupped oysters (Magallana bilineata) and green mussels (Perna viridis) collected in the Philippines

BMC Research Notes

卷:19

Research Note

Abigail S. Rustia¹  Leslie Michelle M. Dalmacio²  Erniel B. Barrios³  Patricia Mae M. Lagazon¹  John Carlo G. Gosilatar⁴  Dennis D. Tanay⁴  Anne Marie M. Matubis-Binuya⁵  Christrhea N. Udang⁵  Minerva M. Manaog⁵  Roel Anthony S. Bayangos¹  Denise Anne B. Dela Cruz¹  Crisanto M. Lopez^5,6 

[1] School of Business, Monash University Malaysia, Bandar Sunway Selangor Darul Ehsan, 47500, Selangor, Malaysia

[2] Microbiology Services Laboratory, Institute of Pure and Applied Chemistry, 1108, Quezon City, Philippines

[3] Department of Biology, School of Science and Engineering, Ateneo de Manila University, 1108, Quezon City, Metro Manila, Philippines

[4] Department of Food Science and Nutrition, College of Home Economics, University of the Philippines Diliman, 1101, Quezon City, Metro Manila, Philippines

[5] College of Medicine, University of the Philippines Manila, 1000, Manila, Metro Manila, Philippines

[6] National Fisheries Development Center, Bureau of Fisheries and Aquatic Resources, 2400, Dagupan City, Pangasinan, Philippines

关键词: Hepatitis a virus;    HAV;    Green mussels;    Perna viridis;    Oyster;    Magallana bilineata;    Philippines;   

DOI  :  10.1186/s13104-025-07481-z

 received in 2025-01-31, accepted in 2025-09-02,  发布年份 2026

来源: Springer

【 摘 要 】

ObjectivesHepatitis A virus (HAV) causes acute hepatitis through ingestion of contaminated food and water, with bivalve molluscs as common vehicles of transmission. As filter feeders, HAV concentrates in their digestive tissues when grown in contaminated waters. In 2020, the Philippines produced nearly 75 MT of shellfish. However, maintaining proper sanitation in growing areas remains challenging, and data on the occurrence of HAV in these commercially significant shellfish is lacking. This study aimed to detect HAV in Philippine cupped oysters (Magallana bilineata), green mussels (Perna viridis), and seawater from their growing areas. Samples were collected in Pangasinan (August 2022), Cavite (April 2023), and Capiz (June 2023), and HAV detection was conducted using quantitative reverse transcription polymerase chain reaction (RT-qPCR).ResultsHAV RNA was not detected in the shellfish and seawater samples, consistent with zero reported cases of Hepatitis A during the collection periods. However, a disparity was noted between these findings and potential sewage run-off linked to net positive rainfall. The Department of Health reported 111 and 127 Hepatitis A cases nationwide in 2022 and 2023, respectively, indicating that HAV remains endemic. Identifying sources, transmission modes, and environmental factors is crucial for integrating HAV risks into the food safety risk assessment framework.

【 授权许可】

CC BY-NC-ND   
© The Author(s) 2025

【 图 表 】

Fig. 2