Postoperative Margin Management After Conventional Excision of Facial Basal and Squamous Cell Carcinomas: A Histotype-Specific Framework

Journal of Skin Cancer

卷:2026

Research Article

Flavio Perottino¹  Stefano Ottoboni²  Giulia Dalmasso¹  Katia Barbaro³  Daniele Sagrafoli³  Paola Ghisellini²  Cristina Rando²  Roberto Eggenhöffner²  Mario Borgione¹ 

[1] Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy, unige.it

[2] Department of ENT and Stomatology, Centre Hospitalier des Escartons, Briancon, France

[3] Experimental Zooprophylactic Institute of Lazio and Tuscany, Rome, Italy

关键词: basal cell carcinoma;    conventional excision;    facial reconstruction;    non-melanoma skin cancer;    postoperative surveillance;    recurrence;    skin cancer;    squamous cell carcinoma;    surgical margins;   

DOI  :  10.1155/jskc/9952281

 received in 2026-06-07, accepted in 2026-07-17,  发布年份 2026

来源: Hindawi Publishing Corporation

【 摘 要 】

BackgroundPostoperative management of close or positive margins after conventional excision of facial nonmelanoma skin cancer is challenging, especially in elderly patients and anatomically constrained sites where re-excision may impose functional or aesthetic morbidity.MethodsWe retrospectively analysed 238 facial carcinoma cases treated by conventional excision at a peripheral ENT unit, including 172 basal cell carcinomas (BCC) and 66 squamous cell carcinomas (SCC). Margins were classified as clear, close or positive. Outcomes were analysed descriptively; two-sided Fisher exact tests were used as exploratory descriptors of distributional imbalance under sparse-event conditions, not as tests of treatment superiority or equivalence.ResultsIn BCC, no recurrence occurred after clear margins (0/90). Among non-clear-margin BCCs, recurrence remained uncommon after structured surveillance (5/65) and early re-excision (1/17). In SCC, recurrence occurred only after positive margins (3/15), with none after clear or close margins.ConclusionThe findings support histotype-specific postoperative interpretation of margin status after conventional facial skin cancer excision. In this cohort, selected lower-risk BCC cases were managed through structured surveillance, whereas SCC recurrence was confined to positive-margin cases, supporting a lower threshold for timely re-excision or equivalent oncologic management when clinically feasible.

【 授权许可】

CC BY   
Copyright © 2026 Flavio Perottino et al. Journal of Skin Cancer published by John Wiley & Sons Ltd. 2026

【 图 表 】

Figure 15