Evaluation of an aortic valve prosthesis: Fluid-structure interaction or structural simulation?

JOURNAL OF BIOMECHANICS

卷:58

Article

Luraghi, Giulia¹  Wu, Wei¹  De Gaetano, Francesco¹  Matas, Jose Felix Rodriguez¹  Moggridge, Geoff D.²  Serrani, Marta²  Stasiak, Joanna²  Costantino, Maria Laura¹  Migliavacca, Francesco¹ 

[1] Politecn Milan, Dept Chem Mat & Chem Engn Giulio Natta, Lab Biol Struct Mech LaBS, Milan, Italy

[2] Univ Cambridge, Dept Chem Engn & Biotechnol, Cambridge, England

关键词: Fluid-structure interaction;    Polymeric heart valve;    Finite element analysis;    Cardiovascular mechanics;   

DOI  :  10.1016/j.jbiomech.2017.04.004

来源: Elsevier

【 摘 要 】

Bio-inspired polymeric heart valves (PHVs) are excellent candidates to mimic the structural and the fluid dynamic features of the native valve. PHVs can be implanted as prosthetic alternative to currently clinically used mechanical and biological valves or as potential candidate for a minimally invasive treatment, like the transcatheter aortic valve implantation. Nevertheless, PHVs are not currently used for clinical applications due to their lack of reliability. In order to investigate the main features of this new class of prostheses, pulsatile tests in an in-house pulse duplicator were carried out and reproduced in silico with both structural Finite-Element (FE) and Fluid-Structure interaction (FSI) analyses. Valve kinematics and geometric orifice area (GOA) were evaluated to compare the in vitro and the in silico tests. Numerical results showed better similarity with experiments for the FSI than for the FE simulations. The maximum difference between experimental and FSI GOA at maximum opening time was only 5%, as compared to the 46.5% between experimental and structural FE GOA. The stress distribution on the valve leaflets clearly reflected the difference in valve kinematics. Higher stress values were found in the FSI simulations with respect to those obtained in the FE simulation. This study demonstrates that FSI simulations are more appropriate than FE simulations to describe the actual behaviour of PHVs as they can replicate the valve-fluid interaction while providing realistic fluid dynamic results. (C) 2017 The Authors. Published by Elsevier Ltd.

【 授权许可】

Free