Computational wear simulation of patellofemoral articular cartilage during in vitro testing

JOURNAL OF BIOMECHANICS

卷:44

Article

Li, Lingmin¹  Patil, Shantanu²  Steklov, Nick²  Bae, Won³  Temple-Wong, Michele³  D'Lima, Darryl D.²  Sah, Robert L.³  Fregly, Benjamin J.¹ 

[1] Univ Florida, Dept Mech & Aerosp Engn, Gainesville, FL 32611 USA

[2] Scripps Clin, Shiley Ctr Orthopaed Res & Educ, La Jolla, CA 92037 USA

[3] Univ Calif San Diego, Dept Bioengn, La Jolla, CA 92093 USA

关键词: Computational modeling;    Wear simulation;    Articular cartilage;    Contact analysis;    Biomechanics;   

DOI  :  10.1016/j.jbiomech.2011.03.012

来源: Elsevier

【 摘 要 】

Though changes in normal joint motions and loads (e.g., following anterior cruciate ligament injury) contribute to the development of knee osteoarthritis, the precise mechanism by which these changes induce osteoarthritis remains unknown. As a first step toward identifying this mechanism, this study evaluates computational wear simulations of a patellofemoral joint specimen wear tested on a knee simulator machine. A multibody dynamic model of the specimen mounted in the simulator machine was constructed in commercial computer-aided engineering software. A custom elastic foundation contact model was used to calculate contact pressures and wear on the femoral and patellar articular surfaces using geometry created from laser scan and MR data. Two different wear simulation approaches were investigated-one that wore the surface geometries gradually over a sequence of 10 one-cycle dynamic simulations (termed the progressive approach), and one that wore the surface geometries abruptly using results from a single one-cycle dynamic simulation (termed the non-progressive approach). The progressive approach with laser scan geometry reproduced the experimentally measured wear depths and areas for both the femur and patella. The less costly non-progressive approach predicted deeper wear depths, especially on the patella, but had little influence on predicted wear areas. Use of MR data for creating the articular and subchondral bone geometry altered wear depth and area predictions by at most 13%. These results suggest that MR-derived geometry may be sufficient for simulating articular cartilage wear in vivo and that a progressive simulation approach may be needed for the patella and tibia since both remain in continuous contact with the femur. (C) 2011 Elsevier Ltd. All rights reserved.

【 授权许可】

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