Estimating absolute aortic pressure using MRI and a one-dimensional model

JOURNAL OF BIOMECHANICS

卷:47

Article

Khalife, Maya¹  Decoene, Astrid²  Caetano, Filipa²  de Rochefort, Ludovic¹  Durand, Emmanuel¹  Rodriguez, Dima¹ 

[1] Univ Paris 11, CNRS, UMR 8081, Imagerie Resonance Magnet Med & Multimodalites IR, F-91405 Orsay, France

[2] Univ Paris 11, CNRS, UMR 8628, Lab Math Orsay, F-91405 Orsay, France

关键词: Cardiovascular imaging;    MRI;    Aorta;    Blood pressure;    One-dimensional model;    Compliance;    Non-invasive;   

DOI  :  10.1016/j.jbiomech.2014.07.018

来源: Elsevier

【 摘 要 】

Aortic blood pressure is a strong indicator to cardiovascular diseases and morbidity. Clinically, pressure measurements are done by inserting a catheter in the aorta. However, imaging techniques have been used to avoid the invasive procedure of catheterization. In this paper, we combined MRI measurements to a one-dimensional model in order to simulate blood flow in an aortic segment. Absolute pressure was estimated in the aorta by using MRI measured flow as boundary conditions and MRI measured compliance as a pressure law for solving the model. Model computed pressure was compared to catheter measured pressure in an aortic phantom. Furthermore, aortic pressure was estimated in vivo in three healthy volunteers. (C) 2014 Elsevier Ltd. All rights reserved.

【 授权许可】

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