Manifold learning based data-driven modeling for soft biological tissues

JOURNAL OF BIOMECHANICS

卷:117

Article

He, Qizhi^1,2  Laurence, Devin W.³  Lee, Chung-Hao^3,4  Chen, Jiun-Shyan¹ 

[1] Univ Calif San Diego, Dept Struct Engn, La Jolla, CA 92093 USA

[2] Pacific Northwest Natl Lab, Phys & Computat Sci Directorate, Richland, WA 99354 USA

[3] Univ Oklahoma, Sch Aerosp & Mech Engn, Biomech & Biomat Design Lab, Norman, OK 73019 USA

[4] Univ Oklahoma, Inst Biomed Engn Sci & Technol, Norman, OK 73019 USA

关键词: Data-driven material modeling;    Manifold learning;    Mitral heart valve;    Hyperelasticity;    Local convexity data-driven method;   

DOI  :  10.1016/j.jbiomech.2020.110124

来源: Elsevier

【 摘 要 】

Data-driven modeling directly utilizes experimental data with machine learning techniques to predict a material's response without the necessity of using phenomenological constitutive models. Although data driven modeling presents a promising new approach, it has yet to be extended to the modeling of large deformation biological tissues. Herein, we extend our recent local convexity data-driven (LCDD) framework (He and Chen, 2020) to model the mechanical response of a porcine heart mitral valve posterior leaflet. The predictability of the LCDD framework by using various combinations of biaxial and pure shear training protocols are investigated, and its effectiveness is compared with a full structural, phenomenological model modified from Zhang et al. (2016) and a continuum phenomenological Fung-type model (Tong and Fung, 1976). We show that the predictivity of the proposed LCDD nonlinear solver is generally less sensitive to the type of loading protocols (biaxial and pure shear) used in the data set, while more sensitive to the insufficient coverage of the experimental data when compared to the predictivity of the two selected phenomenological models. While no pre-defined functional form in the material model is necessary in LCDD, this study reinstates the importance of having sufficiently rich data coverage in the date-driven and machine learning type of approaches. It is also shown that the proposed LCDD method is an enhancement over the earlier distance-minimization data-driven (DMDD) against noisy data. This study demonstrates that when sufficient data is available, data-driven computing can be an alternative method for modeling complex biological materials. (c) 2020 Elsevier Ltd. All rights reserved.

【 授权许可】

Free