Development of Ti-15Zr-Mo alloys for applying as implantable biomedical devices

JOURNAL OF ALLOYS AND COMPOUNDS

卷:749

Article

Correa, D. R. N.^1,5  Kuroda, P. A. B.^2,5  Lourenco, M. L.^2,5  Fernandes, C. J. C.⁴  Buzalaf, M. A. R.³  Zambuzzi, W. F.^4,5  Grandini, C. R.^2,5 

[1] IFSP Fed Inst Educ Sci & Technol, BR-18095410 Sorocaba, SP, Brazil

[2] UNESP Univ Estadual Paulista, Lab Anelasticidade & Biomat, BR-17033360 Bauru, SP, Brazil

[3] Univ Sao Paulo, Fac Odontol, Dept Ciencias Biol, BR-17012901 Bauru, SP, Brazil

[4] UNESP Univ Estadual Paulista, Dept Quim & Bioquim, BR-18618970 Botucatu, SP, Brazil

[5] IBTN Br Inst Biomat Tribocorros & Nanomed, Brazilian Branch, BR-17033360 Bauru, SP, Brazil

关键词: Titanium alloys;    Microstructure;    Mechanical properties;    Biomaterial;   

DOI  :  10.1016/j.jallcom.2018.03.308

来源: Elsevier

【 摘 要 】

In this study, the effect of molybdenum content in Ti-15Zr-based alloys (wt%) was analyzed in terms of crystalline structure, microstructure, selected mechanical properties, and cytotoxicity. The samples were produced by argon arc-melting followed by hot rolling and heat treatment processes. The crystalline structure and microstructure were dependent of both alloying elements (zirconium and molybdenum). Ti-15Zr alloy displayed only laths of alpha ' phase, while the alloys up to Ti-15Zr-10Mo exhibited different proportions of alpha ', alpha '', and beta phases. Molybdenum content higher than 12.5 wt% fully stabilized the beta phase. Vickers microhardness values of Ti-15Zr-Mo alloys were higher than those of CP-Ti due to solid solution and phase precipitation strengthening. Young's modulus values of Ti-15Zr-Mo alloys were lower than those of CP-Ti due to b phase stabilization. Cytotoxicity levels of Ti-15Zr-Mo alloys were within a tolerable range for biomedical purposes. In addition, we observed molybdenum content in Ti-15Zr-based alloys promoted an increase on pre-osteoblast adhesion up to 3 h of adhesion's time. Thus, Ti-15Zr-15Mo alloy presented better combination of properties than some traditional metallic biomaterials. (C) 2018 Elsevier B. V. All rights reserved.

【 授权许可】

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