Does major depressive disorder with somatic delusions constitute a distinct subtype of major depressive disorder with psychotic features?

JOURNAL OF AFFECTIVE DISORDERS

卷:112

Article

Kamara, Taafi S.^2,3  Whyte, Ellen M.^2,3  Mulsant, Benoit H.^1,2,3,4  Peasley-Miklus, Catherine^5,6  Rothschild, Anthony J.^7,8  Flint, Alastair J.^4,9,10,11  Heo, Moonseong^5,6  Papadernetriou, Eros^5,6  Mathis, Erin R.^2,3  Meyers, Barnett S.^5,6 

[1] Ctr Addict & Mental Hlth, Geriatr Mental Hlth Program, Toronto, ON M6J 1H4, Canada

[2] Univ Pittsburgh, Sch Med, Western Psychiat Inst & Clin, Pittsburgh, PA 15260 USA

[3] Univ Pittsburgh, Sch Med, Dept Psychiat, Pittsburgh, PA 15260 USA

[4] Univ Toronto, Dept Psychiat, Toronto, ON M5S 1A1, Canada

[5] Cornell Univ, Weill Med Coll, Dept Psychiat, Ithaca, NY 14853 USA

[6] New York Presbyterian Hosp Westchester, New York, NY USA

[7] Univ Massachusetts, Sch Med, Dept Psychiat, Amherst, MA 01003 USA

[8] Univ Massachusetts Mem HealthCare, Worcester, MA USA

[9] Univ Hlth Network, Toronto, ON, Canada

[10] Toronto Rehabil Inst, Geriatr Program & Res Inst, Toronto, ON, Canada

[11] Toronto Gen Res Inst, Toronto, ON, Canada

关键词: Depression;    Psychosis;    Somatization;    Psychotic depression;    Delusions;    Subtype;   

DOI  :  10.1016/j.jad.2008.04.008

来源: Elsevier

【 摘 要 】

Background: Among patients with major depression with psychotic features, little is known about the extent to which those with and without somatic delusions differ. Methods: The first 183 participants in the STOP-PD study were divided into two groups based on the presence or absence of somatic delusions and were compared on multiple demographic and clinical characteristics. Results: In the multivariate analysis, those with somatic delusions reported more somatic symptoms, rated their health as worse, and were less likely to have persecutory delusions. Conclusions: Based on the methods we used, we could not detect meaningful differences between subjects with and without somatic delusions. This suggests that the presence of irrational somatic ideation does not define a distinct clinical subgroup among patients with psychotic depression. This finding needs to be replicated. (C) 2008 Elsevier B.V. All rights reserved.

【 授权许可】

Free