Mood disorders in eating disorder patients: Prevalence and chronology of ONSET

JOURNAL OF AFFECTIVE DISORDERS

卷:185

Article

Godart, N.^1,2,3  Radon, L.^1,3  Curt, F.¹  Duclos, J.¹  Perdereau, F.¹  Lang, F.⁴  Venisse, J. L.⁵  Halfon, O.⁶  Bizouard, P.⁷  Loas, G.⁸  Corcos, M.¹  Jeammet, Ph.¹  Flament, M. F.⁹ 

[1] Inst Mutualiste Montsouris, Dept Psychiat, F-75014 Paris, France

[2] Paris Descartes Univ, Fac Med, Paris, France

[3] INSERM, U669, Paris, France

[4] Univ Hosp Ctr St Etienne, Psychiat Serv, St Etienne, France

[5] St Jacques Hosp, Addict Unit, Nantes, France

[6] Univ Child & Adolescent Psychiat Serv, SUPEA Dept Res, Lausanne, Switzerland

[7] Univ Besancon Hosp Ctr, F-25030 Besancon, France

[8] CHS P Pinel, Univ Hosp Sect, Amiens, France

[9] Royal Ottawa Hosp, Inst Mental Hlth Res, Youth Program, Ottawa, ON K1Z 7K4, Canada

关键词: Eating disorders;    Anorexia nervosa;    Bulimia;    Mood disorders;    Comorbidity;    Age of onset;   

DOI  :  10.1016/j.jad.2015.06.039

来源: Elsevier

【 摘 要 】

Objectives: In a clinical population, we estimated the frequency of mood disorders among 271 patients suffering from Anorexia Nervosa (AN) and Bulimia Nervosa (RN) in comparison to a control group matched for age and gender. Method: The frequency of mood disorders was measured using the Mini International Neuropsychiatric Interview (MINI), DSM-IV version. Results: Mood disorders were more frequent among eating disorder (ED) patients than among controls, with a global prevalence of the order of 80% for each ED group. The majority of the mood disorders comorbid with ED were depressive disorders (MDD and clysthymia). The relative chronology of onset of these disorders was equivocal, because mood disorders in some cases preceded and in others followed the onset of the eating disorders. Limitations: Our sample was characterized by patients with severe ED and high comorbidities, and thus do not represent the entire population of AN or BN. This also may have resulted in an overestimation of prevalence Conclusion: Mood disorders appear significantly more frequently in patients seeking care for ED than in controls. These results have implications for the assessment and treatment of ED patients, and for the aetiopathogenesis of these disorders. (C) 2015 Elsevier B.V. All rights reserved.

【 授权许可】

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