Insomnia late in pregnancy is associated with perinatal anxiety: A longitudinal cohort study

JOURNAL OF AFFECTIVE DISORDERS

卷:248

Article

Osnes, Rannveig S.^1,2  Roaldset, John Olav^1,2,3  Follestad, Turid⁴  Eberhard-Gran, Malin^5,6,7 

[1] More Romsdal Hlth Trust, Alesund Hosp, Dept Psychiat, Alesund, Norway

[2] Norwegian Univ Sci & Technol, Dept Mental Hlth, Fac Med & Hlth Sci, Trondheim, Norway

[3] Oslo Univ Hosp, Ctr Res & Educ Forens Psychiat, Oslo, Norway

[4] Norwegian Univ Sci & Technol, Dept Publ Hlth & Nursing, Fac Med & Hlth Sci, Trondheim, Norway

[5] Akershus Univ Hosp, Res Unit, HOKH, Lorenskog, Norway

[6] Inst Clin Med, Campus Ahus, Lorenskog, Norway

[7] Eastern & Southern Norway, Dept Infant Mental Hlth, Reg Ctr Child & Adolescent Mental Hlth, Oslo, Norway

关键词: Anxiety;    Insomnia;    Pregnancy;    Perinatal;    Postpartum;    Risk factors;   

DOI  :  10.1016/j.jad.2019.01.027

来源: Elsevier

【 摘 要 】

Background: Postpartum anxiety (PPA) affects a substantial number of women. Despite increasing recognition of PPA, few studies have focused on perinatal anxiety and potential PPA triggers. Here we aimed to estimate the prevalence of perinatal anxiety disorders, and to explore the association between insomnia during late pregnancy and anxiety before and after childbirth. Methods: This study was part of the large population-based Akershus Birth Cohort. We analyzed data from the hospital's birth records and questionnaire responses from pregnancy weeks 17 and 32 and postpartum week 8 (n= 1563). Perinatal anxiety symptoms were measured using the Hopkins Symptom Check List. Anxiety disorder measurements were based on questions from the Mini-International Neuropsychiatric Interview. Insomnia was measured using the Bergen Insomnia Scale. Results: Among perinatal women, 10% reported symptoms of at least one anxiety disorder. The observed prevalence of obsessive-compulsive disorder was higher after delivery (4.2%) than during pregnancy (2.5%). Multiple regression analysis, with adjustment for several psychosocial and reproductive variables, indicated that insomnia during pregnancy was significantly associated with postpartum anxiety symptoms. However, this association was markedly weakened when depression variables were included in the analysis, indicating that gestational insomnia may also be a marker for a mood disorder. Limitations: Immigrant and single women were underrepresented in our sample. Conclusions: Our results suggest that anxiety disorders are prevalent during the perinatal period. Moreover, insomnia during pregnancy is associated with perinatal anxiety. Health professionals should be aware that women with gestational insomnia may have an increased risk of mood and anxiety disorders.

【 授权许可】

Free