Relationship between sedentary behavior and depression: A mediation analysis of influential factors across the lifespan among 42,469 people in low-and middle-income countries

JOURNAL OF AFFECTIVE DISORDERS

卷:229

Article

Stubbs, Brendon^1,2,3  Vancampfort, Davy^4,5  Firth, Joseph^6,7  Schuch, Felipe B.^8,9,10  Hallgren, Mats¹¹  Smith, Lee¹²  Gardner, Benjamin¹³  Kahl, Kai. G.¹⁴  Veronese, Nicola¹⁵  Solmi, Marco^16,17  Carvalho, Andre F.^18,19  Koyanagi, Ai^20,21 

[1] South London & Maudsley NHS Fdn Trust, Physiotherapy Dept, Denmark Hill, London SE5 8AZ, England

[2] Kings Coll London, Inst Psychiat Psychol & Neurosci, Hlth Serv & Populat Res Dept, De Crespigny Pk, London SE5 8AF, England

[3] Anglia Ruskin Univ, Fac Hlth Social Care & Educ, Chelmsford, Essex, England

[4] Katholieke Univ Leuven, Dept Rehabil Sci, Leuven, Belgium

[5] Katholieke Univ Leuven, Univ Psychiat Ctr, Leuven Kortenberg, Belgium

[6] Univ Western Sydney, NICM, Sch Hlth & Sci, Sydney, NSW, Australia

[7] Univ Manchester, Fac Biol Med & Hlth, Div Psychol & Mental Hlth, Manchester, Lancs, England

[8] Unilasalle, Canoas, Brazil

[9] Escola Educ Fis Fisioterapia & Danca, Porto Alegre, RS, Brazil

[10] Univ Fed Rio Grande do Sul, Hosp Clin Porto Alegre, Dept Psychiat, Porto Alegre, RS, Brazil

[11] Karolinska Inst, Dept Publ Hlth Sci, Stockholm, Sweden

[12] Anglia Ruskin Univ, Cambridge Ctr Sport & Exercise Sci, Dept Life Sci, Cambridge, England

[13] Kings Coll London, Inst Psychiat Psychol & Neurosci, Dept Psychol, Addison House,Guys Campus, London SE1 1UL, England

[14] Hannover Med Sch, Dept Psychiat Social Psychiat & Psychotherapy, Carl Neuberg Str 1, D-30625 Hannover, Germany

[15] CNR, Neurosci Inst, Aging Branch, Padua, Italy

[16] Univ Padua, Dept Neurosci, Padua, Italy

[17] Mental Hlth Dept, Local Hlth Unit 17, ULSS 17, Padua, Italy

[18] Univ Fed Ceara, Dept Clin Med, Fortaleza, Ceara, Brazil

[19] Univ Fed Ceara, Fac Med, Translat Psychiat Res Grp, Fortaleza, Ceara, Brazil

[20] Univ Barcelona, Res & Dev Unit, Fundacio St Joan de Deu, Parc Sanitari St Joan de Deu,Dr Antoni Pujadas 42, Barcelona 08830, Spain

[21] Inst Salud Carlos III, CIBERSAM, Monforte Lemos 3-5 Pabellon 11, Madrid 28029, Spain

关键词: Sedentary behavior;    Sitting;    Physical activity;    Depression;    Low-and middle-income countries;   

DOI  :  10.1016/j.jad.2017.12.104

来源: Elsevier

【 摘 要 】

Background: Sedentary behavior (SB) is associated with diabetes, cardiovascular disease and low mood. There is a paucity of multi-national research investigating SB and depression, particularly among low-and middle-income countries. This study investigated the association between SB and depression, and factors which influence this. Methods: Cross-sectional data were analyzed from the World Health Organization's Study on Global Ageing and Adult Health. Depression was based on the Composite International Diagnostic Interview. The association between depression and SB (self-report) was estimated by multivariable linear and logistic regression analyses. Mediation analysis was used to identify influential factors. Results: A total of 42,469 individuals (50.1% female, mean 43.8 years) were included. People with depression spent 25.6 (95% CI8.5-42.7) more daily minutes in SB than non-depressed participants. This discrepancy was most notable in adults aged >= 65 y (35.6 min more in those with depression). Overall, adjusting for sociodemographics and country, depression was associated with a 1.94 (95% CI1.31-2.85) times higher odds for high SB (i.e., >= 8 h/day). The largest proportion of the SB-depression relationship was explained by mobility limitations (49.9%), followed by impairments in sleep/ energy (43.4%), pain/discomfort (31.1%), anxiety (30.0%), disability (25.6%), cognition (16.1%), and problems with vision (11.0%). Other health behaviors (physicalactivity, alcohol consumption, smoking), body mass index, and social cohesion did not influence the SB-depression relationship. Conclusion: People with depression are at increased risk of engaging in high levels of SB. This first multi- national study offers potentially valuable insight for a number of hypotheses which may influence this relationship, although testing with longitudinal studies is needed.

【 授权许可】

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