Relative impact of Axis I mental disorders on quality of life among adults in the community

JOURNAL OF AFFECTIVE DISORDERS

卷:131

Article

Guan, Bingqing^2,3  Deng, Yunlong²  Cohen, Patricia^1,4  Chen, Henian^1,4,5 

[1] New York State Psychiat Inst & Hosp, New York, NY 10032 USA

[2] Cent S Univ, Xiangya Hosp 3, Dept Clin Psychol, Changsha, Hunan, Peoples R China

[3] Tianjin Med Univ, Canc Inst & Hosp, Dept Pain Management, Tianjin, Peoples R China

[4] Columbia Univ, Coll Phys & Surg, Dept Psychiat, New York, NY 10027 USA

[5] SUNY Stony Brook, Sch Med, Stony Brook, NY USA

关键词: Depression;    Anxiety;    Quality of life;    Personality disorder;   

DOI  :  10.1016/j.jad.2011.01.010

来源: Elsevier

【 摘 要 】

Background: Little is known about the relative impact of different mental disorders on adult quality of life (QOL). This study estimated associations between several mental disorders and QOL in a representative American community sample. Methods: The QOL instrument was administered to 640 adult participants in the Children in the Community Study, a population-based longitudinal study. DSM-Axis I and Axis II mental disorder diagnoses were assessed by psychiatric interview. Results: Poorer QOL was strongly associated with having a mood disorder, especially major depression disorder (MOD) (effect size, ES = -0.57, p < 0.01), whereas poorer quality social relationships were associated with having dysthymia and bipolar disorders (ES = -0.92, p < 0.01; ES = -0.80, p < 0.05, respectively). Most anxiety disorders were not independently related to QOL with the exception of post traumatic stress disorder (PTSD), which was significantly related to poorer physical health (ES = -0.78, p < 0.01) and psychological wellbeing (ES = -0.73, p < 0.01) and to less overall QOL (ES = -0.57, p < 0.01). Conclusions: MDD and PTSD are independently related to impaired QOL and dysthymia and bipolar disorder negatively influence social relationships. (C) 2011 Elsevier B.V. All rights reserved.

【 授权许可】

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