Handgrip strength and depression among 34,129 adults aged 50 years and older in six low- and middle-income countries

JOURNAL OF AFFECTIVE DISORDERS

卷:243

Article

Ashdown-Franks, Garcia^1,2  Stubbs, Brendon^2,3  Koyanagi, Ai^4,5  Schuch, Felipe^6,7  Firth, Joseph^8,9  Veronese, Nicola¹⁰  Vancampfort, Davy^11,12 

[1] Kings Coll London, Inst Psychiat Med Psychol & Neurosci, Dept Psychol Med, De Crespigny Pk, London SE5 8AF, England

[2] Univ Toronto, Dept Exercise Sci, 55 Harbord St, Toronto, ON M5S 2W6, Canada

[3] South London & Maudsley NHS Fdn Trust, Physiotherapy Dept, Denmark Hill, London SE5 8AZ, England

[4] Univ Barcelona, Res & Dev Unit, Fundacio St Joan de Deu, Parc Sanitari St Joan de Deu,Dr Antoni Pujadas 42, Barcelona 08830, Spain

[5] Inst Salud Carlos III, Ctr Invest Biomed Red Salud Mental, CIBERSAM, Monforte Lemos 3-5 Pabellon 11, Madrid 28029, Spain

[6] La Salle Univ, Canoas, Brazil

[7] Univ Fed Rio Grande do Sul, Hosp Clin Porto Alegre, Porto Alegre, RS, Brazil

[8] Univ Western Sydney, Sch Sci & Hlth, NICM Hlth Res Inst, Sydney, NSW, Australia

[9] Univ Manchester, Fac Biol Med & Hlth, Div Psychol & Mental Hlth, Manchester, Lancs, England

[10] CNR, Neurosci Inst, Aging Branch, Padua, Italy

[11] Katholieke Univ Leuven, Dept Rehabil Sci, Tervuursevest 101, B-3001 Leuven, Belgium

[12] Katholieke Univ Leuven, Univ Psychiat Ctr, Leuvensesteenweg 517, B-3070 Kortenberg, Belgium

关键词: Hand grip strength;    Depression;    Older adults;    Health;    Mental health;   

DOI  :  10.1016/j.jad.2018.09.036

来源: Elsevier

【 摘 要 】

Introduction: Handgrip strength is a simple and inexpensive marker of health and mortality risk. It presents an ideal risk-stratifying method for use in low and middle-income countries (LMICs). There are, however, no population-based studies investigating the associations between handgrip strength and depression in LMICs. We aimed to assess these associations among community-dwelling middle-aged and older adults using nationally representative data from six LMICs. Method: Cross-sectional data on individuals aged >= 50 years from the World Health Organization's Study on Global Ageing and Adult Health were analyzed. Depression was based on the Composite International Diagnostic Interview. Weak handgrip strength was defined as < 30 kg for men and < 20 kg for women using the average value of two handgrip measurements of the dominant hand. Multivariable logistic regression analysis was conducted. Results: The sample included 34,129 individuals (62.4 +/- 16.0 years; 52.1% female). The prevalence of weak handgrip strength and depression were 47.4% and 6.2%, respectively. Individuals with weak handgrip strength had a higher prevalence of depression than those without this condition (8.8% vs. 3.8%; p < 0.001). Across all countries, after adjustment for potential confounders, weak handgrip strength was associated with a 1.45 (95% CI = 1.12-1.88) times higher odds for depression, although some between-country differences were noted. Discussion: Weaker handgrip strength is associated with higher odds for depression in LMICs. Future research should seek to establish the predictive value of this inexpensive measure for clinical use. Furthermore, interventional studies should examine if muscular strength can be a target of resistance-training interventions to address depressive symptoms in low-resourced settings.

【 授权许可】

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