Breast Arterial Calcium A Game Changer in Women's Cardiovascular Health?

JACC-CARDIOVASCULAR IMAGING

卷:12

Review

Quispe, Renato¹  Al-Rifai, Mahmoud^1,2  Di Carlo, Philip A.³  Michos, Erin D.^1,4,5  Amin, Nivee P.⁶  Kianoush, Sina^1,7  Handy, Catherine E.^1,8  McEvoy, John W.^1,4  Blaha, Michael J.^1,5  Nasir, Khurram^1,9  Blumenthal, Roger S.¹  Tota-Maharaj, Rajesh¹  Lima, Joao A. C.¹⁰  Comin-Colet, Josep^11,12,13  Cainzos-Achirica, Miguel^1,11,12,14 

[1] Johns Hopkins Med Inst, Johns Hopkins Ciccarone Ctr Prevent Heart Dis, Dept Cardiol, Baltimore, MD 21205 USA

[2] Univ Kansas, Sch Med, Dept Med, Wichita, KS 67214 USA

[3] Johns Hopkins Med Inst, Russell H Morgan Dept Radiol & Radiol Sci, Breast Imaging Div, 600 N Wolfe St, Baltimore, MD 21205 USA

[4] Johns Hopkins Bloomberg Sch Publ Hlth, Welch Ctr Prevent Epidemiol & Clin Res, Baltimore, MD USA

[5] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA

[6] Weill Cornell Med Coll, Div Cardiol, New York, NY USA

[7] Yale Univ, Sch Med, New Haven, CT USA

[8] Johns Hopkins Univ, Sidney Kimmel Comprehens Canc Ctr, Baltimore, MD USA

[9] Baptist Hlth South Florida, Ctr Prevent & Wellness, Miami, FL USA

[10] Johns Hopkins Med Inst, Dept Cardiol, Cardiac Imaging Unit, Baltimore, MD 21205 USA

[11] Bellvitge Univ Hosp, Cardiol Dept, Barcelona, Spain

[12] Bellvitge Biomed Res Inst, Barcelona, Spain

[13] Univ Barcelona, Dept Clin Sci, Barcelona, Spain

[14] Res Triangle Inst Hlth Solut, Pharmacoepidemiol & Risk Management, Barcelona, Spain

关键词: breast artery calcium;    cardiovascular disease;    risk assessment;    screening;    women;    women's health;   

DOI  :  10.1016/j.jcmg.2018.07.035

来源: Elsevier

【 摘 要 】

In 2018, cardiovascular disease (CVD) was the leading cause of death among women, and current CVD prevention paradigms may not be sufficient in this group. In that context, it has recently been proposed that detection of calcification in breast arteries may help improve CVD risk screening and assessment in apparently healthy women. This review provides an overview of breast arterial anatomy; and the epidemiology, pathophysiology, and measurement of breast artery calcium (BAC); and discusses the features of the BAC-CVD link. The potential clinical applications that BAC may offer for CVD prevention in the context of current clinical practice guidelines and recommendations are also discussed. Finally, current gaps in evidence gaps are outlined, and future directions in the field are explored with a focus on the implementation of BAC mammography as a CVD risk-screening tool in routine clinical practice. (C) 2019 by the American College of Cardiology Foundation.

【 授权许可】

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