Nerve growth factor delivery systems

JOURNAL OF CONTROLLED RELEASE

卷:53

Article; Proceedings Paper

Haller, MF ; Saltzman, WM

关键词: controlled release;    polymer;    growth factors;    nerve growth factor;    epidermal growth factor;    morphogen;    cell transplantation;    Alzheimer's disease;   

DOI  :  10.1016/S0168-3659(97)00232-0

来源: Elsevier

【 摘 要 】

Growth factors encourage tissue regeneration and differentiation, accelerate wound healing, and modulate neural repair. Thus, growth factor administration may become a useful treatment for neurodegenerative diseases, such as Alzheimer's disease or Parkinson's disease, which are characterized by the degeneration of neuronal cell populations. Controlled-release polymer delivery systems may be an important technology in enabling the prevention of neuronal degeneration, or even the stimulation of neuronal regeneration, by providing a sustained release of growth factors to promote the long-term survival of endogenous or transplanted cells. (C) 1998 Elsevier Science B.V.

【 授权许可】

Free