Self-oscillating gel as novel biomimetic materials

JOURNAL OF CONTROLLED RELEASE

卷:140

Article; Proceedings Paper

Yoshida, Ryo¹  Sakai, Takamasa¹  Hara, Yusuke²  Maeda, Shingo²  Hashimoto, Shuji²  Suzuki, Daisuke¹  Murase, Yoko^1,3 

[1] Univ Tokyo, Grad Sch Engn, Dept Mat Engn, Bunkyo Ku, Tokyo 1138656, Japan

[2] Waseda Univ, Grad Sch Sci & Engn, Dept Appl Phys, Shinjuku Ku, Tokyo 1698555, Japan

[3] Dai Nippon Printing Co Ltd, Nano Sci Res Ctr, Res Planning Dept, Tsukuba, Ibaraki 3002646, Japan

关键词: Polymer gels;    Smart materials;    Self-oscillation;    Biomimetics;   

DOI  :  10.1016/j.jconrel.2009.04.029

来源: Elsevier

【 摘 要 】

Stimuli-responsive polymers and their application to biomaterials have been widely studied. On the other hand, as a novel biomimetic polymer, we have been studying the polymer with an autonomous self-oscillating function by utilizing oscillating chemical reactions. So far, we succeeded in developing a novel self-oscillating polymer and gels by utilizing the oscillating reaction, called the Belousov-Zhabotinsky (BZ) reaction, which is recognized as a chemical model for understanding several autonomous phenomena in biological systems. The self-oscillating polymer is composed of poly(N-isopropylacrylamide) (PNIPAAm) network in which the catalyst for the BZ reaction is covalently immobilized. Under the coexistence of the reactants, the polymer undergoes spontaneous cyclic soluble-insoluble changes or swelling-deswelling changes (in the case of gel) without any on-off switching of external stimuli. In this paper, our recent studies on the self-oscillating polymer gels and the design of functional material systems using the polymer are summarized. (C) 2009 Elsevier B.V. All rights reserved

【 授权许可】

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