Diagnostic testing and interpretation of tests for autoimmunity

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

卷:125

Article

Castro, Christine¹  Gourley, Mark¹ 

[1] NIAMSD, NIH, Bethesda, MD 20892 USA

关键词: Autoimmune;    disease;    laboratory;    inflammatory markers;    evaluation;    rheumatic;    serologies;    flow cytometry;    HLA;    organ specific;   

DOI  :  10.1016/j.jaci.2009.09.041

来源: Elsevier

【 摘 要 】

Laboratory testing is of great value when evaluating a patient with a suspected autoimmune disease. The results can confirm a diagnosis, estimate disease severity, aid in assessing prognosis and are useful for following disease activity. Components of the laboratory examination include a complete blood count with differential, a comprehensive metabolic panel, measurement of inflammatory markers and autoantibodies, and flow cytometry. This chapter discusses these components and includes a discussion about organ-specific immunologic diseases for which immunologic laboratory testing is used. Comprehensive laboratory evaluation of a suspected autoimmune illness in conjunction with a thorough clinical evaluation provides a better understanding of a patient's immunologic disease. (J Allergy Clin Immunol 2010;125:S238-47.)

【 授权许可】

Free