Air pollution and lung function in children

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

卷:148

Review

Garcia, Erika¹  Rice, Mary B.²  Gold, Diane R.^3,4 

[1] Univ Southern Calif, Dept Prevent Med, Los Angeles, CA 90007 USA

[2] Harvard Med Sch, Div Pulm & Crit Care Med, Dept Med, Beth Israel Deaconess Med Ctr, Boston, MA 02115 USA

[3] Harvard TH Chan Sch Publ Hlth, Dept Environm Hlth, Boston, MA USA

[4] Harvard Med Sch, Channing Div Network Med, Brigham & Womens Hosp, Boston, MA 02115 USA

关键词: Children;    lung function;    FEV1;    FVC;    air pollution;    wildfire;    gas stoves;    biomass;   

DOI  :  10.1016/j.jaci.2021.05.006

来源: Elsevier

【 摘 要 】

In this narrative review, we summarize the literature and provide updates on recent studies of air pollution exposures and child lung function and lung function growth. We include exposures to outdoor air pollutants that are monitored and regulated through air quality standards, and air pollutants that are not routinely monitored or directly regulated, including wildfires, indoor biomass and coal burning, gas and wood stove use, and volatile organic compounds. Included is a more systematic review of the recent literature on long-term air pollution and child lung function because this is an indicator of future adult respiratory health and exposure assessment tools have improved dramatically in recent years. We present summary observations and knowledge gaps. We end by discussing what is known about what can be done at the individual/household, local/regional, and national levels to overcome structural impediments, reduce air pollution exposures, and improve child lung function. We found a large literature on adverse air pollution effects on children's lung function level and growth; however, many questions remain. Important areas needing further research include whether early-life effects are fixed or reversible; and what are windows of increased susceptibility, long-term effects of repeated wildfire events, and effects of air quality interventions.

【 授权许可】

Free