Controlled uptake and release of imatinib from ultrasound nanoparticles Cu3(BTC)2 metal-organic framework in comparison with bulk structure

JOURNAL OF COLLOID AND INTERFACE SCIENCE

卷:471

Article

Abbasi, Amir Reza¹  Rizvandi, Maryam¹  Azadbakht, Azadeh²  Rostamnia, Sadegh³ 

[1] Razi Univ, Fac Chem, Kermanshah 67194, Iran

[2] Islamic Azad Univ, Khorramabad Branch, Dept Chem, Khorramabad, Iran

[3] Univ Maragheh, Dept Chem, ONG, POB 55181-83111, Maragheh, Iran

关键词: Nanoparticles;    Imatinib;    Ultrasound;    Metal-organic frameworks;   

DOI  :  10.1016/j.jcis.2016.03.018

来源: Elsevier

【 摘 要 】

The porosity of metal-organic frameworks (MOFs) is an important point concerning the possible use of such functional materials for different purposes. In this work, we study uptake and release properties of imatinib (IM) from nano Cu(lI)-MOF in comparison with bulk Cu(II)-MOF. To explore the absorption ability of the Cu(II)-MOF to IM, fresh sample of Cu-3(BTC)(2) was immersed in an aqueous solution of IM and were monitored in real time with UV/vis spectroscopy. Results show that the adsorbed quantity of IM over nano Cu-3(BTC)(2) (I) is much higher than those over a bulk Cu-3(BTC)(2) (II). (C) 2016 Published by Elsevier Inc.

【 授权许可】

Free