The effects on diet, anastomotic type, and loxiglumide on gastric emptying following gastrojejunostomy

INTERNATIONAL JOURNAL OF SURGERY

卷:7

Article

Yucel, Tayfun²  Gonullu, Dogan¹  Gurer, Ahmet Orhan³  Duzman, Ruhan⁴  Koksoy, Ferda Nihat¹  Yilmaz, Necati⁵  Sit, Mustafa⁶ 

[1] Taksim Training & Res Hosp, Dept Surg, Minist Hlth, TR-34433 Istanbul, Turkey

[2] Sakarya Univ, Sakarya Med Sch, Dept Surg, Sakarya, Turkey

[3] Birecik State Hosp, Minist Hlth, Dept Surg, Birecik, Urfa, Turkey

[4] Elazig State Hosp, Minist Hlth, Dept Surg, Elazig, Turkey

[5] Taksim Training & Res Hosp, Minist Hlth, Dept Nucl Med, TR-34433 Istanbul, Turkey

[6] Dogubayazit State Hosp, Dept Surg, Minist Hlth, Agri, Turkey

关键词: Antecolic or retrocolic gastrojejunostomy;    Normal diet;    Early high-calorie-hyperosmolar diet;    Loxiglumide;    Gastric emptying;    Scintigraphy;   

DOI  :  10.1016/j.ijsu.2009.01.010

来源: Elsevier

【 摘 要 】

Purpose: The effects on gastric emptying of feeding with a normal diet (ND), an early high-calorie and hyperosmolar diet (HCHOD) or normal diet plus intraperitoneal loxiglumide (LOX) were investigated in rats with antecolic (ACGJ) or retrocolic (RCGJ) gastrojejunostomy. Methods: Sixty rats were separated into six groups of ten animals each (ACGJ + ND, RCGJ + ND, ACGJ + HCHOD, RCGJ + HCHOD, ACGJ + ND + LOX, and RCGJ + ND + LOX). On the seventh day, scintigraphic measurements of solid gastric emptying were made at 1, 30 and 60 min. Results: According to the 60-min results, the RCGJ + ND group exhibited delayed emptying compared to the ACGJ + ND group (p = 0.023). Gastric emptying of ACGJ + HCHOD rats was delayed compared with the other ACGJ groups (compared to ACGJ + ND: p = 0.000, and ACGJ + ND + LOX: p = 0.015). Gastric emptying was more effective in the RCGJ + ND + LOX group than the other RCGJ groups (compared to RCGJ + ND: p = 0.003, and RCGJ + HCHOD: p = 0.001). Conclusion: Antecolic gastrojejunostomy provided better gastric emptying. An early high-calorie and hyperosmolar enteral diet delayed gastric emptying in both types of anastomosis. (C) 2009 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.

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