Surgical outcomes of pancreaticoduodenectomy in young patients: A case series

INTERNATIONAL JOURNAL OF SURGERY

卷:44

Article

El Nakeeb, Ayman¹  El Sorogy, Mohamed¹  Salem, Ali¹  Said, Rami¹  El Dosoky, Mohamed¹  Moneer, Ahmed¹  Ali, Mahmoud Abdelwahab¹  Mahdy, Youssef¹ 

[1] Mansoura Univ, Gastroenterol Surg Ctr, Mansoura 35516, Egypt

关键词: Pancreaticoduodenectomy;    Periampullary neoplasms;    Pancreatic exocrine and endocrine function;    Solid pseudopapillary tumor;    Delayed gastric emptying;   

DOI  :  10.1016/j.ijsu.2017.07.024

来源: Elsevier

【 摘 要 】

Background: Pancreaticoduodenectomy (PD) is a complex procedure for management periampullary neoplasms The aim of our work is to report the surgical outcomes after PD in young adult (YA) (< 35 years) and to compare it to a adult patients who underwent PD. Methods: We retrospectively analyzed the data of all patients who underwent PD in the period from January 1993 to December 2016. The primary outcome was the rate of total postoperative complications. Secondary outcomes included postoperative pathology, exocrine and endocrine function and survival rate. Results: 58/975 patients (5.9%) were YA and the majority of them were females. The incidence of postoperative complications in the YA was comparable to that in the adult group. Delayed gastric emptying developed significantly in adult group than YA group (0.008). The overall survival was significantly higher in the YA (P = 0.0001). The most common pathology in the YA was adenocarcinoma (41.4%) and solid pseudopapillary tumor (SPT) (29.3%). No significant difference as regards postoperative pancreatic exocrine and endocrine function in both groups. Conclusion: PD in YA when performed in tertiary centers with good surgical experience is safe. The most common pathological diagnosis in the YA was adenocarcinoma followed by SPT. (C) 2017 IJS Publishing Group Ltd. Published by Elsevier Ltd. All rights reserved.

【 授权许可】

Free