The function of serotonin within the liver

JOURNAL OF HEPATOLOGY

卷:48

Review

Ruddell, Richard G.¹  Mann, Derek A.²  Ramm, Grant A.¹ 

[1] PO Royal Brisbane & Womens Hosp, Queensland Inst Med Res, Hepat Fibrosis Grp, Brisbane, Qld 4029, Australia

[2] Newcastle Univ, Inst Cellular Med, Liver Grp, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England

关键词: 5-hydroxytryptamine/serotonin;    liver;    innervation;    haemodynamics;    wound healing;   

DOI  :  10.1016/j.jhep.2008.01.006

来源: Elsevier

【 摘 要 】

Serotonin or 5-hydroxytryptamine (5-HT) is known to regulate several key aspects of liver biology and these functions include hepatic blood flow, innervation and wound healing. Given the importance of these functions it is surprising that relatively little time has been dedicated to studying the precise function and mechanisms of serotonin within the liver. Here we describe what is known about serotonin and the liver and those receptor types that mediate the observed effects with an aim to stimulating new interest in the field of serotonin and liver biology. (C) 2008 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.

【 授权许可】

Free