Slurry sampling in serum blood for mercury determination by CV-AFS

JOURNAL OF HAZARDOUS MATERIALS

卷:161

Article

Aranda, Pedro R.^1,2  Gil, Raul A.^1,2  Moyano, Susana¹  De Vito, Irma¹  Martinez, Luis D.^1,2 

[1] Univ Nacl San Luis, Fac Quim Bioquim & Farm, Dept Quim Analit, RA-5700 San Luis, Argentina

[2] Inst Quim San Luis INQUISAL CONICET, RA-5700 San Luis, Argentina

关键词: Slurry sampling;    Human serum blood;    Mercury;    Atomic fluorescence spectrometry;   

DOI  :  10.1016/j.jhazmat.2008.04.129

来源: Elsevier

【 摘 要 】

The heavy metal mercury (Hg) is a neurotoxin known to have a serious health impact even at relatively low concentrations. A slurry method was developed for the sensitive and precise determination of mercury in human serum blood samples by cold vapor generation coupled to atomic fluorescence spectrometry (CV-AFS). All variables related to the slurry formation were studied. The optimal hydrochloric concentration and tin(II) chloride concentration for CV generation were evaluated. Calibration within the range 0.1-10 mu g L-1 Hg was performed with the standard addition method, and compared with an external calibration. Additionally, the reliability of the results obtained was evaluated by analyzing mercury in the same samples, but submitted to microwave-assisted digestion method. The limit of detection was calculated as 25 ng L-1 and the relative standard deviation was 3.9% at levels around of 0.4 mu g L-1 Hg. (c) 2008 Elsevier B.V. All rights reserved.

【 授权许可】

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