Bisphenol A and its analogs in muscle and liver of fish from the North East Atlantic Ocean in relation to microplastic contamination. Exposure and risk to human consumers

JOURNAL OF HAZARDOUS MATERIALS

卷:393

Article

Barboza, Luis Gabriel A.^1,2  Cunha, Sara C.³  Monteiro, Carolina³  Fernandes, Jose O.³  Guilhermino, Lucia^1,2 

[1] Univ Porto, ICBAS Inst Biomed Sci Abel Salazar, Dept Populat Study, Lab Ecotoxicol & Ecol ECOTOX, Rua Jorge Viterbo Ferreira 228, P-4050313 Porto, Portugal

[2] Univ Porto, CIIMAR CIMAR LA Interdisciplinary Ctr Marine & En, Res Grp Ecotoxicol Stress Ecol & Environm Hlth EC, Av Gen Norton De Matos S-N, P-4450208 Matosinhos, Portugal

[3] Univ Porto, Fac Pharm, Lab Bromatol & Hydrol, LAQV REQUIMTE, Rua Jorge De Viterbo Ferreira 228, P-4050313 Porto, Portugal

关键词: Microplastics;    Bisphenols;    Plastic additives;    Food safety;    Human health;   

DOI  :  10.1016/j.jhazmat.2020.122419

来源: Elsevier

【 摘 要 】

In the present study, the levels of bisphenol A (BPA) and analagous compounds in muscle and liver of fish (Dicentrarchus labrax, Trachurus trachurus, Scomber colias) from the North East Atlantic Ocean were determined and the risk of their consumption by humans was assessed. The potential relationship between bisphenol concentrations and microplastic (MP) contamination of fish was also investigated. Fish from all the species had BPA in the liver and muscle, and bisphenol B (BPB) and bisphenol E (BPE) in the muscle. The highest concentration of BPA in the liver (302 ng/g dry weight - dw) was found in S. colias and the lowest one (5 ng/g dw) in T. trachurus. In the muscle, the bisphenol with the highest concentration was BPE in S. colias (272 ng/g dw). Fish with microplastics had significantly higher concentrations of bisphenols than fish where no microplastics were found, suggesting a relation between MP and bisphenol contamination in fish. In all species, the concentration of bisphenols was correlated with higher MP intake. Regarding human food safety, the estimated daily intake (EDI), target hazard quotient (THQ) and hazard index (HI) of bisphenols were higher than those established by the European Food Safety Authority suggesting hazardous risk for human consumers. These findings highlight the need of more research on fish contamination by MP and associated chemicals and inherent human food safety risks.

【 授权许可】

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