ADHD and accidents over the life span-A systematic review

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

卷:125

Review

Brunkhorst-Kanaan, Nathalie¹  Libutzki, Berit²  Reif, Andreas¹  Larsson, Henrik^3,4  McNeill, Rhiannon V.⁵  Kittel-Schneider, Sarah^1,5 

[1] Goethe Univ, Univ Hosp Frankfurt, Dept Psychiat Psychotherapy & Psychosomat Med, Heinrich Hoffmann Str 10, D-60528 Frankfurt, Germany

[2] Univ Groningen, Univ Med Ctr Groningen, Dept Psychiat, Interdisciplinary Ctr Psychopathol & Emot Regulat, Groningen, Netherlands

[3] Karolinska Inst, Dept Med Epidemiol & Biostat, Box 281, S-17177 Stockholm, Sweden

[4] Orebro Univ, Sch Med Sci, Campus USO, S-70182 Orebro, Sweden

[5] Univ Hosp Wurzburg, Dept Psychiat Psychotherapy & Psychosomat Med, Margarete Hoppel Pl 1, D-97082 Wurzburg, Germany

关键词: ADHD;    Accidents;    Injuries;    Stimulant;    Methylphenidate;    Atomoxetine;    Amphetamine;    Trajectories;   

DOI  :  10.1016/j.neubiorev.2021.02.002

来源: Elsevier

【 摘 要 】

Studies have demonstrated an increased risk of accidents and injuries in children, adolescents and adults with attention-deficit/hyperactivity disorder (ADHD). However, little is known about how accident risk may alter over the lifespan. Additionally, it would be important to know if the most common types of accidents and injuries differ in ADHD patients over different age groups. Furthermore, there is increasing evidence of an ameliorating effect of ADHD medication on accident risk. Lastly, the underlying risk factors and causal mechanisms behind increased accident risk remain unclear. We therefore conducted a systematic review focusing on the above described research questions. Our results suggested that accident/injury type and overall risk changes in ADHD patients over the lifespan. ADHD medication appeared to be similarly effective at reducing accident risk in all age groups. However, studies with direct comparisons of accident/injuries and effects of medication at different age groups or in old age are still missing. Finally, comorbidities associated with ADHD such as substance abuse appear to further increase the accident/injury risk.

【 授权许可】

Free