Towards a human self-regulation system: Common and distinct neural signatures of emotional and behavioural control

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

卷:90

Review

Langner, Robert^1,2  Leiberg, Susanne^3,4  Hoffstaedter, Felix^1,2  Eickhoff, Simon B.^1,2 

[1] Heinrich Heine Univ Dusseldorf, Med Fac, Inst Syst Neurosci, D-40225 Dusseldorf, Germany

[2] Res Ctr Julich, Inst Neurosci & Med INM Brain & Behav 7, D-52425 Julich, Germany

[3] Univ Zurich, Dept Econ, Lab Social & Neural Syst Res, CH-8006 Zurich, Switzerland

[4] Ambulatorium Lenzburg Klin Hasel, CH-5600 Lenzburg, Switzerland

关键词: Cognitive control;    Emotion regulation;    Executive functions;    ALE meta-analysis;    Resting-state fMRI;    Functional decoding;    Control theory;   

DOI  :  10.1016/j.neubiorev.2018.04.022

来源: Elsevier

【 摘 要 】

Self-regulation refers to controlling our emotions and actions in the pursuit of higher-order goals. Although research suggests commonalities in the cognitive control of emotion and action, evidence for a shared neural substrate is scant and largely circumstantial. Here we report on two large-scale meta-analyses of human neuroimaging studies on emotion or action control, yielding two fronto-parieto-insular networks. The networks' overlap, however, was restricted to four brain regions: posteromedial prefrontal cortex, bilateral anterior insula, and right temporo-parietal junction. Conversely, meta-analytic contrasts revealed major between-network differences, which were independently corroborated by clustering domain-specific regions based on their intrinsic functional connectivity, as well as by functionally characterizing network sub-clusters using the BrainMap database for quantitative forward and reverse inference. Collectively, our analyses identified a core system for implementing self-control across emotion and action, beyond which, however, either regulation facet appears to rely on broadly similar yet distinct subnetworks. These insights into the neurocircuitry subserving affective and executive facets of self-control suggest both processing commonalities and differences between the two aspects of human self-regulation.

【 授权许可】

Free