Are unimanual movements bilateral?

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

卷:113

Review

Chettouf, Sabrina^1,2,3,4,5,6  Rueda-Delgado, Laura M.⁷  de Vries, Ralph⁸  Ritter, Petra^1,2,3,4,9,10  Daffertshofer, Andreas^5,6 

[1] Charite Univ Med Berlin, Berlin, Germany

[2] Free Univ Berlin, Berlin, Germany

[3] Humboldt Univ, Berlin, Germany

[4] Berlin Inst Hlth, Dept Neurol, Brain Simulat Sect, Berlin, Germany

[5] Vrije Univ, Fac Behav & Movement Sci, Amsterdam Movement Sci, Amsterdam, Netherlands

[6] Vrije Univ, Fac Behav & Movement Sci, Inst Brain & Behav Amsterdam, Amsterdam, Netherlands

[7] Trinity Coll Dublin, Trinity Coll, Inst Neurosci, Dublin, Ireland

[8] Vrije Univ, Med Lib, Amsterdam, Netherlands

[9] Bernstein Ctr Computat Neurosci Berlin, Berlin, Germany

[10] Berlin Inst Hlth, Berlin, Germany

关键词: Unimanual;    Interhemispheric;    Motor cortex;    Motor coordination;    Corpus callosum;    Bilateral activation;    Electroencephalography (EEG);    Magnetoencephalography (MEG);    Transcranial magnetic stimulation (TMS);    Functional magnetic resonance imaging (fMRI);    Structural MRI;   

DOI  :  10.1016/j.neubiorev.2020.03.002

来源: Elsevier

【 摘 要 】

Motor control is a fundamental challenge for the central nervous system. In this review, we show that unimanual movements involve bi-hemispheric activation patterns that resemble the bilateral neural activation typically observed for bimanual movements. For unimanual movements, the activation patterns in the ipsilateral hemisphere arguably entail processes that serve to suppress interhemispheric cross-talk through transcallosal tracts. Improper suppression may cause involuntary muscle co-activation and as such it comes as no surprise that these processes depend on the motor task. Identifying the detailed contributions of local and global excitatory and inhibitory cortical processes to this suppression calls for integrating findings from various behavioral paradigms and imaging modalities. Doing so systematically highlights that lateralized activity in left (pre)motor cortex modulates with task complexity, independently of the type of task and the end-effector involved. Despite this lateralization, however, our review supports the idea of bi-hemispheric cortical activation being a fundamental mode of upper extremity motor control.

【 授权许可】

Free