Autism spectrum disorder and attention-deficit/hyperactivity disorder in early childhood: A review of unique and shared characteristics and developmental antecedents

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

卷:65

Review

Visser, Janne C.¹  Rommelse, Nanda Nj.^1,2  Greven, Corina U.^1,3,4  Buitelaar, Jan K.^1,3 

[1] Karakter Child & Adolescent Psychiat Univ Ctr, Reinier Postlaan 12, NL-6525 GC Nijmegen, Netherlands

[2] Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, Med Ctr, Dept Psychiat, NL-6525 ED Nijmegen, Netherlands

[3] Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, Med Ctr, Dept Cognit Neurosci, NL-6525 ED Nijmegen, Netherlands

[4] Kings Coll London, MRC, Social Genet & Dev Psychiat Ctr, Inst Psychiat Psychol & Neurosci, London WC2R 2LS, England

关键词: ASD;    ADHD;    Autism;    Infant;    Preschool age;    Attention;    Temperament;    Executive function;    Early developmental pathways;    Early developmental mechanisms;   

DOI  :  10.1016/j.neubiorev.2016.03.019

来源: Elsevier

【 摘 要 】

Autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) have overlapping characteristics and etiological factors, but to which extent this applies to infant- and preschool age is less well understood. Comparing the pathways to ASD and ADHD from the earliest possible stages is crucial for understanding how phenotypic overlap emerges and develops. Ultimately, these insights may guide preventative and therapeutic interventions. Here, we review the literature on the core symptoms, temperament and executive function in ASD and ADHD from infancy through preschool age, and draw several conclusions: (1) the co-occurrence of ASD and ADHD increases with age, severity of symptoms and lower IQ (2) attention problems form a linking pin between early ASD and ADHD, but the behavioral, cognitive and sensory correlates of these attention problems partly diverge between the two conditions, (3) ASD and ADHD share high levels of negative affect, although the underlying motivational and behavioral tendencies seem to differ, and (4) ASD and ADHD share difficulties with control and shifting, but partly opposite behaviors seem to be involved. (C) 2016 Elsevier Ltd. All rights reserved.

【 授权许可】

Free