Toward an understanding of the neural mechanisms underlying dual-task performance: Contribution of comparative approaches using animal models

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

卷:84

Review

Watanabe, Kei^1,2  Funahashi, Shintaro³ 

[1] Natl Inst Informat & Commun Technol NICT, Ctr Informat & Neural Networks CiNet, 1-4 Yamadaoka, Suita, Osaka 5650871, Japan

[2] Osaka Univ, Grad Sch Frontier Biosci, 1-3 Yamadaoka, Suita, Osaka 5650871, Japan

[3] Kyoto Univ, Kokoro Res Ctr, Yoshida Sakyo Ku, 46 Shimoadachi Cho, Kyoto 6068501, Japan

关键词: Dual-task paradigm;    Neuroimaging;    Neuropsychology;    Neurophysiology;    Frontal lobe function;    Working memory;    Capacity limitation;    Animal model;    Comparative cognition;   

DOI  :  10.1016/j.neubiorev.2017.08.008

来源: Elsevier

【 摘 要 】

The study of dual-task performance in human subjects has received considerable interest in cognitive neuroscience because it can provide detailed insights into the neural mechanisms underlying higher-order cognitive control. Despite many decades of research, our understanding of the neurobiological basis of dual-task performance is still limited, and some critical questions are still under debate. Recently, behavioral and neurophysiological studies of dual-task performance in animals have begun to provide intriguing evidence regarding how dual-task information is processed in the brain. In this review, we first summarize key evidence in neuroimaging and neuropsychological studies in humans and discuss possible reasons for discrepancies across studies. We then provide a comprehensive review of the literature on dual-task studies in animals and provide a novel working hypothesis that may reconcile the divergent results in human studies toward a unified view of the mechanisms underlying dual-task processing. Finally, we propose possible directions for future dual-task experiments in the framework of comparative cognitive neuroscience.

【 授权许可】

Free