Why would Parkinson's disease lead to sudden changes in creativity, motivation, or style with visual art?: A review of case evidence and new neurobiological, contextual, and genetic hypotheses

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

卷:100

Review

Louring, Jon O.¹  Ishizu, Tomohiro^2,3  Kutlikova, Hana H.⁴  Doerflinger, Felix²  Haugbol, Steven⁵  Leder, Helmut²  Kupers, Ron¹  Pelowski, Matthew² 

[1] Univ Copenhagen, Dept Neurosssci, BRAINlab, Blegdamsvej 3B, DK-2200 Copenhagen, Denmark

[2] Univ Vienna, Fac Psychol, Dept Basic Psychol Res & Res Methods, Liebiggasse 5, A-1010 Vienna, Austria

[3] UCL, Fac Biosci Cell & Dev Biol, Gower St, London WC1E 6BT, England

[4] Univ Vienna, Fac Psychol, Dept Basic Psychol Res & Res Methods, Neuropsychopharmacol & Biopsychol Unit, Liebiggasse 5, A-1010 Vienna, Austria

[5] Copenhagen Univ Hosp Bispebjerg, Dept Neurol, Bispebjerg Bakke 23, DK-2400 Copenhagen, Denmark

关键词: Parkinson's disease;    Visual creativity;    Artists;    Art making;    Neurobiological bases;    Dopamine system;    Psychopharmacology;    Brain damage;   

DOI  :  10.1016/j.neubiorev.2018.12.016

来源: Elsevier

【 摘 要 】

Parkinson's disease (PD) is a devastating diagnosis with, however, potential for an extremely intriguing aesthetic component. Despite motor and cognitive deficits, an emerging collection of studies report a burst of visual artistic output and alterations in produced art in a subgroup of patients. This provides a unique window into the neurophysiological bases for why and how we might create and enjoy visual art, as well as into general brain function and the nature of PD or other neurodegenerative diseases. However, there has not been a comprehensive organization of literature on this topic. Nor has there been an attempt to connect case evidence and knowledge on PD with present understanding of visual art making in psychology and neuroaesthetics in order to propose hypotheses for documented artistic changes. Here, we collect the current research on this topic, tie this to PD symptoms and neurobiology, and provide new theories focusing on dopaminergic neuron damage, over-stimulation from dopamine agonist therapy, and context or genetic factors revealing the neurobiological basis of the visual artistic brain.

【 授权许可】

Free