Neurofeedback training in major depressive disorder: A systematic review of clinical efficacy, study quality and reporting practices

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

卷:125

Review

Trambaiolli, Lucas R.¹  Kohl, Simon H.^2,3  Linden, David E. J.⁴  Mehler, David M. A.⁵ 

[1] Harvard Med Sch, Div Basic Neurosci, McLean Hosp, Boston, MA 02115 USA

[2] Julich Res Ctr, JARA Inst Mol Neurosci & Neuroimaging INM 11, Julich, Germany

[3] Rhein Westfal TH Aachen, Fac Med, Dept Child & Adolescent Psychiat, Aachen, Germany

[4] Maastricht Univ, Sch Mental Hlth & Neurosci, Fac Hlth Med & Life Sci, Maastricht, Netherlands

[5] Univ Munster, Dept Psychiat, Munster, Germany

关键词: Neurofeedback;    Biofeedback;    Real-time fMRI;    Electroencephalography;    Functional magnetic resonance imaging;    Major depressive disorder;    Self-regulation;    Neuroimaging;   

DOI  :  10.1016/j.neubiorev.2021.02.015

来源: Elsevier

【 摘 要 】

Major depressive disorder (MDD) is the leading cause of disability worldwide. Neurofeedback training has been suggested as a potential additional treatment option for MDD patients not reaching remission from standard care (i.e., psychopharmacology and psychotherapy). Here we systematically reviewed neurofeedback studies employing electroencephalography, or functional magnetic resonance-based protocols in depressive patients. Of 585 initially screened studies, 24 were included in our final sample (N = 480 patients in experimental and N = 194 in the control groups completing the primary endpoint). We evaluated the clinical efficacy across studies and attempted to group studies according to the control condition categories currently used in the field that affect clinical outcomes in group comparisons. In most studies, MDD patients showed symptom improvement superior to the control group(s). However, most articles did not comply with the most stringent study quality and reporting practices. We conclude with recommendations on best practices for experimental designs and reporting standards for neurofeedback training.

【 授权许可】

Free