The effect of non-invasive brain stimulation on executive functioning in healthy controls: A systematic review and meta-analysis

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

卷:125

Review

de Boer, Nina S.^1,2  Schluter, Renee S.¹  Daams, Joost G.³  van der Werf, Ysbrand D.⁴  Goudriaan, Anna E.^1,5  van Holst, Ruth J.¹ 

[1] Univ Amsterdam, Dept Psychiat, Locat AMC, Amsterdam Inst Addict Res,Amsterdam UMC, Amsterdam, Netherlands

[2] Radboud Univ Nijmegen, Dept Philosophy, Nijmegen, Netherlands

[3] Amsterdam UMC, Locat AMC, Med Lib, Amsterdam, Netherlands

[4] Amsterdam UMC, Locat VUmc, Dept Anat & Neurosci, Amsterdam, Netherlands

[5] Mental Hlth Care, Arkin & Jellinek, Amsterdam, Netherlands

关键词: Non-invasive brain stimulation;    Transcranial magnetic stimulation;    Transcranial electrical current stimulation;    Executive functioning;    Working memory;    Inhibition;    Flexibility;    Planning;    Initiation;    Meta-analysis;    Healthy individuals;   

DOI  :  10.1016/j.neubiorev.2021.01.013

来源: Elsevier

【 摘 要 】

In recent years, there has been a heightened interest in the effect of non-invasive brain stimulation on executive functioning. However, there is no comprehensive overview of its effects on different executive functioning domains in healthy individuals. Here, we assessed the state of the field by conducting a systematic review and metaanalysis on the effectiveness of non-invasive brain stimulation (i.e. repetitive transcranial magnetic stimulation and transcranial direct current stimulation) over prefrontal regions on tasks assessing working memory, inhibition, flexibility, planning and initiation performance. Our search yielded 63 studies (n = 1537), and the effectiveness of excitatory and inhibitory non-invasive brain stimulation were assessed per executive functioning task. Our analyses showed that excitatory non-invasive brain stimulation had a small but positive effect on Stop Signal Task and Go/No-Go Task performance, and that inhibitory stimulation had a small negative effect on Flanker Task performance. Non-invasive brain stimulation did not affect performance on working memory and flexibility tasks, and effects on planning tasks were inconclusive.

【 授权许可】

Free