Mapping sign-tracking and goal-tracking onto human behaviors

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

卷:111

Review

Colaizzi, Janna M.¹  Flagel, Shelly B.²  Joyner, Michelle A.³  Gearhardt, Ashley N.³  Stewart, Jennifer L.¹  Paulus, Martin P.¹ 

[1] Laureate Inst Brain Res, 6655 S Yale Ave, Tulsa, OK 74136 USA

[2] Univ Michigan, Mol & Behav Neurosci Inst, 205 Zina Pitcher Pl, Ann Arbor, MI 48109 USA

[3] Univ Michigan, Dept Psychol, 530 Church St, Ann Arbor, MI 48109 USA

关键词: Sign-tracking;    Goal-tracking;    Addictive behavior;    Impulse control disorders;    Humans;    Rodents;   

DOI  :  10.1016/j.neubiorev.2020.01.018

来源: Elsevier

【 摘 要 】

As evidenced through classic Pavlovian learning mechanisms, environmental cues can become incentivized and influence behavior. These stimulus-outcome associations are relevant in everyday life but may be particularly important for the development of impulse control disorders including addiction. Rodent studies have elucidated specific learning profiles termed 'sign-tracking' and 'goal-tracking' which map onto individual differences in impulsivity and other behaviors associated with impulse control disorders' etiology, course, and relapse. Whereas goal-trackers are biased toward the outcome, sign-trackers fixate on features that are associated with but not necessary for achieving an outcome; a pattern of behavior that often leads to escalation of reward-seeking that can be maladaptive. The vast majority of the sign- and goal-tracking research has been conducted using rodent models and very few have bridged this concept into the domain of human behavior. In this review, we discuss the attributes of sign- and goal-tracking profiles, how these are manifested neurobiologically, and how these distinct learning styles could be an important tool for clinical interventions in human addiction.

【 授权许可】

Free