The effectiveness of hypnosis for pain relief: A systematic review and meta-analysis of 85 controlled experimental trials

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

卷:99

Review

Thompson, Trevor¹  Terhune, Devin B.²  Oram, Charlotte¹  Sharangparni, Joseph¹  Rouf, Rommana¹  Solmi, Marco³  Veronese, Nicola⁴  Stubbs, Brendon^5,6 

[1] Univ Greenwich, Fac Educ & Hlth, London SE9 2UG, England

[2] Goldsmiths Univ London, Dept Psychol, London, England

[3] Univ Padua, Dept Neurosci, Padua, Italy

[4] CNR, Neurosci Dept, Aging Branch, Padua, Italy

[5] South London & Maudsley NHS Fdn Trust, Physiotherapy Dept, London SE5 8AZ, England

[6] Kings Coll London, Dept Psychol Med, De Crespigny Pk, London SE5 8AF, England

关键词: Pain;    Hypnosis;    Analgesia;    Review;    Meta-analysis;    Suggestion;   

DOI  :  10.1016/j.neubiorev.2019.02.013

来源: Elsevier

【 摘 要 】

The current meta-analysis aimed to quantify the effectiveness of hypnosis for reducing pain and identify factors that influence efficacy. Six major databases were systematically searched for trials comparing hypnotic inductions with no-intervention control conditions on pain ratings, threshold and tolerance using experimentally evoked pain models in healthy participants. Eighty-five eligible studies (primarily crossover trials) were identified, consisting of 3632 participants (hypnosis no = o2892, control no = o2646). Random effects meta-analysis found analgesic effects of hypnosis for all pain outcomes (go = o0.54-0.76, p's < .001). Efficacy was strongly influenced by hypnotic suggestibility and use of direct analgesic suggestion. Specifically, optimal pain relief was obtained for hypnosis with direct analgesic suggestion administered to high and medium suggestibles, who respectively demonstrated 42% (po < o.001) and 29% (po < o.001) clinically meaningful reductions in pain. Minimal benefits were found for low suggestibles. These findings suggest that hypnotic intervention can deliver meaningful pain relief for most people and therefore may be an effective and safe alternative to pharmaceutical intervention. High quality clinical data is, however, needed to establish generalisability in chronic pain populations.

【 授权许可】

Free