Functional reorganization in obstructive sleep apnoea and insomnia: A systematic review of the resting-state fMRI

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

卷:77

Review

Khazaie, Habibolah¹  Veronese, Mattia²  Noori, Khadijeh¹  Emamian, Farnoosh^1,3  Zarei, Mojtaba^4,5  Ashkan, Keyoumars^2,6  Leschziner, Guy D.^2,7  Eickhoff, Claudia R.^8,9  Eickhoff, Simon B.^8,10  Morrell, Mary J.^11,12  Osorio, Ricardo S.¹³  Spiegelhalder, Kai¹⁴  Tahmasian, Masoud^1,4,5  Rosenzweig, Ivana^2,7 

[1] Kermanshah Univ Med Sci, Sleep Disorders Res Ctr, Kermanshah, Iran

[2] Kings Coll London, Dept Neuroimaging, Sleep & Brain Plast Ctr, IoPPN, London, England

[3] Univ Social Welf & Rehabil Sci, Dept Psychiat, Tehran, Iran

[4] Shahid Beheshti Univ, Inst Med Sci & Technol, Tehran, Iran

[5] Inst Res Fundamental Sci IPM, Sch Cognit Sci, Tehran, Iran

[6] Kings Coll Hosp London, Dept Neurosurg, London, England

[7] Guys & St Thomas Hosp, Sleep Disorders Ctr, London, England

[8] Res Ctr Julich, Inst Neurosci & Med INM 1, Julich, Germany

[9] Rhein Westfal TH Aachen, Dept Psychiat Psychotherapy & Psychosomat, Aachen, Germany

[10] Heinrich Heine Univ Dusseldorf, Inst Clin Neurosci & Med Psychol, Dusseldorf, Germany

[11] Imperial Coll London, Natl Heart & Lung Inst, Acad Unit Sleep & Breathing, London, England

[12] Royal Brompton & Harefield NHS Fdn Trust, NIHR Resp Dis Biomed Res Unit, Sydney St, London SW3 6NP, England

[13] NYU, Sch Med, Ctr Brain Hlth, New York, NY USA

[14] Univ Freiburg, Med Ctr, Ctr Mental Disorders, Dept Clin Psychol & Psychophysiol Sleep Med, Freiburg, Germany

关键词: Resting-state fMRI;    Obstructive sleep apnea;    Insomnia disorder;    Sleep disorders;    Major depressive disorder;   

DOI  :  10.1016/j.neubiorev.2017.03.013

来源: Elsevier

【 摘 要 】

Functional neuroimaging techniques have accelerated progress in the study of sleep disorders. Considering the striking prevalence of these disorders in the general population, however, as well as their strong bidirectional relationship with major neuropsychiatric disorders, including major depressive disorder, their numbers are still surprisingly low. This review examines the contribution of resting state functional MRI to current understanding of two major sleep disorders, insomnia disorder and obstructive sleep apnoea. An attempt is made to learn from parallels of previous resting state functional neuroimaging findings in major depressive disorder. Moreover, shared connectivity biomarkers are suggested for each of the sleep disorders. Taken together, despite some inconsistencies, the synthesis of findings to date highlights the importance of the salience network in hyperarousal and affective symptoms in insomnia. Conversely, dysfunctional connectivity of the posterior default mode network appears to underlie cognitive and depressive symptoms of obstructive sleep apnoea. (C) 2017 The Authors. Published by Elsevier Ltd.

【 授权许可】

Free