Mathematical modelling of magnetically targeted drug delivery

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS

卷:293

Article; Proceedings Paper

Grief, AD ; Richardson, G

关键词: magnetic targeting;    drug delivery;    shear-induced diffusion;    network model;    magnetic field design;    simulation;   

DOI  :  10.1016/j.jmmm.2005.02.040

来源: Elsevier

【 摘 要 】

A mathematical model for targeted drug delivery using magnetic particles is developed. This includes a diffusive flux of particles arising from interactions between erythrocytes in the microcirculation. The model is used to track particles in a vessel network. Magnetic field design is discussed and we show that it is impossible to specifically target internal regions using an externally applied field. (c) 2005 Elsevier B.V. All rights reserved.

【 授权许可】

Free