Simple and facile approach to synthesize magnetite nanoparticles and assessment of their effects on blood cells

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS

卷:324

Article

Cotica, Luiz F.¹  Freitas, Valdirlei F.¹  Dias, Gustavo S.¹  Santos, Ivair A.¹  Vendrame, Sheila C.²  Khalil, Najeh M.²  Mainardes, Rubiana M.²  Staruch, Margo³  Jain, Menka³ 

[1] Univ Estadual Maringa, Dept Phys, BR-87020900 Maringa, PR, Brazil

[2] Univ Estadual, Ctr Oeste, Dept Pharm, BR-85040080 Guarapuava, PR, Brazil

[3] Univ Connecticut, Dept Phys, Storrs, CT 06269 USA

关键词: Magnetite nanoparticle;    Structural property;    Magnetic property;    Biological effect;   

DOI  :  10.1016/j.jmmm.2011.08.043

来源: Elsevier

【 摘 要 】

In this paper, a very simple and facile approach for the large scale synthesis of uniform and size-controllable single-domain magnetite nanoparticles is reported. These magnetite nanoparticles were synthesized via thermal decomposition of a ferric nitrate/ethylene glycol solution. The structural and morphological properties of the synthesized nanoparticles were carefully studied. Nearly spherical nanoparticles with inverted spinel structure and average particle and crystallite sizes smaller than 20 nm were obtained. The magnetic measurements revealed that magnetite nanoparticles have a magnetic saturation value near that of the bulk magnetite. The erythrocyte cytotoxicity assays showed no hemolytic potential of the samples containing magnetite nanoparticles, indicating no cytotoxic activity on human erythrocytes, which makes these interesting for biotechnological applications. (C) 2011 Elsevier B.V. All rights reserved.

【 授权许可】

Free