Temperature alters the hypothalamic transcription of photoperiod responsive genes in induction of seasonal response in migratory redheaded buntings

MOLECULAR AND CELLULAR ENDOCRINOLOGY

卷:493

Article

Trivedi, Amit Kumar^1,2  Sur, Sayantan¹  Sharma, Aakansha¹  Taufique, S. K. Tahajjul¹  Gupta, Neelu Jain^1,3  Kumar, Vinod¹ 

[1] Univ Delhi, Dept Zool, Delhi 110007, India

[2] Mizoram Univ, Dept Zool, Aizawl, Mizoram, India

[3] CCS Univ, Dept Zool, Meerut 250004, Uttar Pradesh, India

关键词: Gene expression;    Hypothalamus;    Photoperiod;    Seasonal response;    Temperature;   

DOI  :  10.1016/j.mce.2019.110454

来源: Elsevier

【 摘 要 】

We investigated the temperature effects on hypothalamic transcription of genes involved in the induction of photoperiodic response in redheaded buntings. Birds were exposed at 22 and 38 degrees C to 13-h long photoperiods (LP), with controls at 22 degrees C on 8-h short photoperiods (SP). At 22 degrees C, compared to SP, we found higher tshb, eya3 and dio2 and low dio3 and gnih mRNA expressions after a week of LP; concomitant with testis recrudescence this confirmed buntings' responsiveness to LP-induced photostimulation. tshb, dio2 and gnrh mRNA levels were further increased by 2.5 weeks of LP at 38 degrees C. Temperature sensitive trpm8, but not trpv4, bdnf or adcyap1 also showed LP-induced expression at 22 degrees C. Concomitant changes in dnmt3b and tet2 mRNA expressions further suggested epigenetic modification of temperature influence on photoperiodic responses. These results demonstrate the role of temperature in hypothalamic molecular regulation of the photoperiodic gonadal response in seasonally breeding birds.

【 授权许可】

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