Case study and review: Treatment of tricuspid prosthetic valve thrombosis

INTERNATIONAL JOURNAL OF CARDIOLOGY

卷:162

Review

Zhang, David Yi²  Lozier, Jay³  Chang, Richard⁴  Sachdev, Vandana¹  Chen, Marcus Y.¹  Audibert, Jennifer L.¹  Horvath, Keith A.⁵  Rosing, Douglas R.¹ 

[1] NHLBI, Cardiovasc & Pulm Branch, NIH, Bethesda, MD 20892 USA

[2] Univ Miami, Miller Sch Med, Div Internal Med, Miami, FL 33136 USA

[3] NIH, Hematol Serv, Ctr Clin, Bethesda, MD 20892 USA

[4] NIH, Dept Diagnost Radiol, Ctr Clin, Bethesda, MD 20892 USA

[5] NHLBI, Off Director, NIH, Bethesda, MD 20892 USA

关键词: Tricuspid valve;    Prosthetic valve;    Thrombosis, thrombolysis, fibrinolysis;    Ebstein anomaly;    Recombinant tissue plasminogen activator (tPa);    Pannus;   

DOI  :  10.1016/j.ijcard.2011.09.081

来源: Elsevier

【 摘 要 】

Prosthetic valve thrombosis (PVT) is a severe and life-threatening complication of heart valve replacement. Conventional therapy is surgical thrombectomy or valve replacement. Medical thrombolysis is another emerging option. We report the case of a 57 year old woman with a history of Ebstein anomaly who underwent successful treatment of tricuspid prosthetic valve thrombosis with intra-atrial infusion of very low dose recombinant tissue plasminogen activator (tPA). We review the presentation, etiology, diagnosis, and treatment of tricuspid PVT emphasizing a modified medical option as a safe, minimally invasive alternative to surgical intervention or conventional medical therapy for tricuspid valve thrombosis. Published by Elsevier Ireland Ltd.

【 授权许可】

Free