Cutaneous squamous cell carcinoma Incidence, risk factors, diagnosis, and staging

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

卷:78

Article

Que, Syril Keena T.¹  Zwald, Fiona O.²  Schmults, Chrysalyne D.¹ 

[1] Harvard Med Sch, Brigham & Womens Hosp, Dept Dermatol, Boston, MA USA

[2] Georgetown Univ, Medstar Georgetown Melanoma & Skin Canc Ctr, Washington, DC USA

关键词: 5-fluorouracil;    imiquimod;    ingenol mebutate;    acitretin;    American Joint Commission on Cancer;    Brigham and Women's Hospital staging system;    capecitabine;    CDKN2A;    cetuximab;    chemotherapy;    classification;    cSCC;    CT;    cutaneous squamous cell carcinoma;    familial cancer syndromes;    high-risk;    management;    MRI;    N1S3 staging;    nicotinamide;    nivolumab;    NOTCH1;    p53;    PD-1;    pembrolizumab;    photodynamic therapy;    radiation therapy;    Ras;    retinoids;    risk factors;    sentinel lymph node biopsy;    sirolimus;    staging;   

DOI  :  10.1016/j.jaad.2017.08.059

来源: Elsevier

【 摘 要 】

Learning objectives After completing this learning activity, participants should be able to describe the incidence of cSCC and define factors that are independently associated with poor outcomes on multivariate analysis of cSCC; outline the various staging systems for cSCC, the features that upstage a cSCC, and the rate of local recurrence, metastatic disease, and disease specific death at each stage; and identify aggressive cSCC that require further work-up and treatment.

【 授权许可】

Free