Comorbidity screening in hidradenitis suppurativa: Evidence-based recommendations from the US and Canadian Hidradenitis Suppurativa Foundations

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

卷:86

Article

Garg, Amit¹  Malviya, Neeta¹  Strunk, Andrew¹  Wright, Shari¹  Alavi, Afsaneh²  Alhusayen, Raed^2,3,4  Alikhan, Ali⁵  Daveluy, Steven D.⁶  Delorme, Isabelle⁷  Goldfarb, Noah^8,9  Gulliver, Wayne¹⁰  Hamzavi, Iltefat¹¹  Jaleel, Tarannum¹²  Kimball, Alexa B.¹³  Kirby, Joslyn S.¹⁴  Kirchhof, Mark G.^15,16  Lester, Janice¹⁷  Lev-Tov, Hadar¹⁸  Lowes, Michelle A.¹⁹  Micheletti, Robert^20,21  Orenstein, Lauren A.²²  Piguet, Vincent^2,23  Sayed, Christopher²⁴  Tan, Jerry²⁵  Naik, Haley B.²⁶ 

[1] Donald & Barbara Zucker Sch Med Hofstra Northwell, Dept Dermatol, New Hyde Pk, NY 11042 USA

[2] Univ Toronto, Women Coll Hosp, Fac Med, Div Dermatol, Toronto, ON, Canada

[3] Univ Toronto, Dept Med, Toronto, ON, Canada

[4] Univ Toronto, Sunnybrook Res Inst, Toronto, ON, Canada

[5] Sutter Med Fdn, Dept Dermatol, Sacramento, CA USA

[6] Wayne State Univ, Sch Med, Dept Dermatol, Detroit, MI 48201 USA

[7] Dr Isabelle Delorme Inc, Dermatol, Drummondville, PQ, Canada

[8] Minneapolis Vet Affairs Hlth Care Syst, Dept Internal Med, Minneapolis, MN USA

[9] Minneapolis Vet Affairs Hlth Care Syst, Dept Dermatol, Minneapolis, MN USA

[10] Mem Univ Newfoundland, Fac Med, St John, NL, Canada

[11] Henry Ford Hosp, Multicultural Dermatol Ctr, Dept Dermatol, Detroit, MI 48202 USA

[12] Duke Univ, Sch Med, Dept Dermatol, Durham, NC USA

[13] Beth Israel Deaconess Med Ctr, Harvard Med Fac Phys, Boston, MA 02215 USA

[14] Penn State Milton S Hershey Med Ctr, Hershey, PA USA

[15] Univ Ottawa, Fac Med, Div Dermatol, Ottawa, ON, Canada

[16] Ottawa Hosp, Ottawa, ON, Canada

[17] Donald & Barbara Zucker Sch Med Hofstra Northwell, Clin Med Lib, New Hyde Pk, NY 11042 USA

[18] Univ Miami, Miller Sch Med, Dr Phillip Frost Dept Dermatol & Cutaneous Surg, Miami, FL 33136 USA

[19] Rockefeller Univ, 1230 York Ave, New York, NY 10021 USA

[20] Univ Penn, Perelman Sch Med, Dept Dermatol, Philadelphia, PA 19104 USA

[21] Univ Penn, Perelman Sch Med, Dept Med, Philadelphia, PA 19104 USA

[22] Emory Univ, Sch Med, Dept Dermatol, Atlanta, GA 30322 USA

[23] Womens Coll Hosp, Toronto, ON, Canada

[24] Univ N Carolina, Sch Med, Dept Dermatol, Chapel Hill, NC 27515 USA

[25] Univ Western Ontario, Dept Internal Med, Windsor Campus, Windsor, ON, Canada

[26] Univ Calif San Francisco, Dept Dermatol, San Francisco, CA USA

关键词: acne;    cardiovascular disease;    comorbidity;    Crohn's disease;    depression;    dermatologist;    diabetes mellitus;    dissecting cellulitis of the scalp;    down syndrome;    dyslipidemia;    generalized anxiety disorder;    guidelines;    herpes zoster;    hidradenitis suppurativa;    hypertension;    inflammatory bowel disease;    lymphoma;    metabolic syndrome;    North America;    obesity;    pilonidal disease;    polycystic ovary syndrome;    pyoderma gangrenosum;    screening;    sexual dysfunction;    smoking;    spondyloarthritis;    substance use;    suicide;    systemic;    ulcerative colitis;   

DOI  :  10.1016/j.jaad.2021.01.059

来源: Elsevier

【 摘 要 】

Background: Hidradenitis suppurativa (HS) is associated with comorbidities that contribute to poor health, impaired life quality, and mortality risk. Objective: To provide evidence-based screening recommendations for comorbidities linked to HS. Methods: Systematic reviews were performed to summarize evidence on the prevalence and incidence of 30 comorbidities in patients with HS relative to the general population. The screening recommendation for each comorbidity was informed by the consistency and quality of existing studies, disease prevalence, and magnitude of association, as well as benefits, harms, and feasibility of screening. The level of evidence and strength of corresponding screening recommendation were graded by using the Strength of Recommendation Taxonomy (SORT) criteria. Results: Screening is recommended for the following comorbidities: acne, dissecting cellulitis of the scalp, pilonidal disease, pyoderma gangrenosum, depression, generalized anxiety disorder, suicide, smoking, substance use disorder, polycystic ovary syndrome, obesity, dyslipidemia, diabetes mellitus, metabolic syndrome, hypertension, cardiovascular disease, inflammatory bowel disease, spondyloarthritis, and sexual dysfunction. It is also recommended to screen patients with Down syndrome for HS. The decision to screen for specific comorbidities may vary with patient risk factors. The role of the dermatologist in screening varies according to comorbidity. Limitations: Screening recommendations represent one component of a comprehensive care strategy. Conclusions: Dermatologists should support screening efforts to identify comorbid conditions in HS.

【 授权许可】

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