Measuring atopic eczema symptoms in clinical practice: The first consensus statement from the Harmonising Outcome Measures for Eczema in clinical practice initiative

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

卷:82

Article

Leshem, Yael A.^1,2  Chalmers, Joanne R.³  Apfelbacher, Christian^4,5  Furue, Masutaka⁶  Gerbens, Louise A. A.⁷  Prinsen, Cecilia A. C.⁸  Schmitt, Jochen⁹  Spuls, Phyllis I.⁷  Thomas, Kim S.³  Williams, Hywel C.³  Simpson, Eric L.¹⁰ 

[1] Rabin Med Ctr, Div Dermatol, Petah Tiqwa, Israel

[2] Tel Aviv Univ, Sackler Sch Med, Tel Aviv, Israel

[3] Univ Nottingham, Ctr Evidence Based Dermatol, Nottingham, England

[4] Univ Regensburg, Med Sociol, Inst Epidemiol & Prevent Med, Regensburg, Germany

[5] Otto von Guericke Univ, Inst Social Med & Hlth Syst Res, Magdeburg, Germany

[6] Kyushu Univ, Dept Dermatol, Fukuoka, Fukuoka, Japan

[7] Univ Amsterdam, Dept Dermatol, Amsterdam UMC, Locat Acad Med Ctr,Amsterdam Publ Hlth Infect & I, Amsterdam, Netherlands

[8] Vrije Univ Amsterdam, Amsterdam UMC, Dept Epidemiol & Biostat, Amsterdam Publ Hlth Res Inst, Amsterdam, Netherlands

[9] Med Fac Carl Gustav Carus, Ctr Evidence Based Healthcare, Dresden, Germany

[10] Oregon Hlth & Sci Univ, Dept Dermatol, Portland, OR 97201 USA

关键词: outcomes;    outcome measures;    instruments;    atopic dermatitis;    atopic eczema;    eczema;    Harmonising Outcome Measures for Eczema;    HOME;    clinical practice;   

DOI  :  10.1016/j.jaad.2019.12.055

来源: Elsevier

【 摘 要 】

Background: Measuring patient-centered outcomes in clinical practice is valuable for monitoring patients and advancing real-world research. A new initiative from the Harmonising Outcome Measures for Eczema (HOME) group aims to recommend what might be recorded for atopic eczema patients in routine clinical care. Objectives: Prioritize outcome domains to measure atopic eczema in clinical practice and select valid and practical outcome measurement instruments for the highest-priority domain. Methods: An online survey of HOME members identified and ranked 21 possible health domains. Suitable instruments were then selected for the top-prioritized domain at the HOME VI meeting, using established consensus processes informed by systematic reviews of instrument quality. Results: Patient-reported symptoms was the top-prioritized domain. In accordance with psychometric properties and feasibility, there was consensus that the recommended instruments to measure atopic eczema symptoms in clinical practice are the POEM, the PO-SCORAD index, or both. The numeric rating scale for itch received support pending definition and validation in atopic eczema. Conclusion: Following the first step of the HOME Clinical Practice initiative, we endorse using the POEM, the PO-SCORAD index, or both for measuring atopic eczema symptoms in clinical practice. Additional high-priority domains for clinical practice will be assessed at subsequent HOME meetings.

【 授权许可】

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